| 1 | RS | Royal Flight of Oman | ICAO: ORF, Callsign: Oman, Name change to Oman Royal Flight. | OM | AVCODES |
| 2 | RS | Aerofreight Airlines, JSC | ICAO: FRT, Callsign: Aerofreight, | RUS | AVCODES |
| 3 | RS | Aerotransportes Entre Rios Srl | ICAO: SFA, Callsign: Aersa, Designator RS recalled by IATA | RA | AVCODES |
| 4 | RS | Sky Regional Airlines, Inc. | ICAO: SKV, Callsign: Sky Regional, IATA Designator changed to KV. | CDN | AVCODES |
| 5 | RS | Oman Royal Flight | ICAO: ORF, Callsign: Oman, Name change from Royal Flight of Oman. | OM | AVCODES |
| 6 | RS | Air Seoul, Inc. | ICAO: ASV, Callsign: Air Seoul, | ROK | AVCODES |
| 7 | RS | Roberval and Saguenay Ry. Co. | 10/1966 & 1/1975-7/2005; eliminated 1/2008 | | NAKINA |
| 8 | RS | Roberval-Saguenay Ry. | 1/1941-4/1970 | | NAKINA |
| 9 | RS | Roberval and Saguenay Ry. Co. | 4/1938 | | NAKINA |
| 10 | RS | Roberval and Saguenay Ry. Co. | Apr-38 | | NRHS |
| 11 | RS | Roberval-Saguenay Ry. | 1/52-4/70 | | NRHS |
| 12 | RS | Roberval and Saguenay Ry. Co. | 10/66 & 1/75-7/2000 | | NRHS |
| 13 | RS | ROBERVAL & SAGUENAY RAILWAY COMPANY | | | PWRC |
| 14 | RS | Roberval and Saguenay Railway | | | RSRV |
| 15 | RS | Roberval and Saguenay Ry. Co. | | USA | TRAFFIC |
| 16 | RS | RS Railspeed SA | | CH | VKM |
| 17 | RS&P | Roscoe, Snyder & Pacific Ry. | 7/1923-4/1938 | | NAKINA |
| 18 | RS&P | Roscoe, Snyder & Pacific Ry. | Apr-38 | | NRHS |
| 19 | RS&P | ROSCOE, SNYDER & PACIFIC RWY. | | | PWRC |
| 20 | RSA | Elisra Airlines | Callsign: Esra, | SUD | AVCODES |
| 21 | RSA | Air Service Affaires | | F | AVCODES |
| 22 | RSA | Elisra Airlines | | | ICAO1 |
| 23 | RSA | REPUBLIC STEEL CO.(ALABAMA) | | | PWRC |
| 24 | RSA | Boliden Mineral AB | | SE | VKM |
| 25 | RSAA | RHINO SPECIALIZED TRANSPORT LLC | | | SCAC4 |
| 26 | RSAC | RAMSAY SCARLETT & CO INC | | | SCAC3 |
| 27 | RSAC | R S TRANSPORT | | | SCAC4 |
| 28 | RSAE | RSA EXPRESS INC | | | SCAC3 |
| 29 | RSAE | RELIANT TRUCK LINES | | | SCAC4 |
| 30 | RSAG | ROSE AGRI-SEED INC | | | SCAC4 |
| 31 | RSAG | Rostocker Straßenbahn AG | City: Rostock | D | TRAFFIC |
| 32 | RSAH | RSA LOGISTICS LLC | | | SCAC4 |
| 33 | RSAI | RESAL INC | | | SCAC3 |
| 34 | RSAM | ROSS, A M ENTERPRISES LTD | | | SCAC4 |
| 35 | RSAO | RAMOS ACOSTA, AYDE | | | SCAC4 |
| 36 | RSAQ | RUBBER SHIPPERS ASSOCIATION INC | | | SCAC3 |
| 37 | RSAR | R S AIR SERVICES | | | SCAC4 |
| 38 | RSAS | ROSAS TRANSPORTADORA S A DE C V | | | SCAC4 |
| 39 | RSAT | R & S AUTO TRANSPORT | | | SCAC3 |
| 40 | RSAT | REYES SANTOS, ARTEMIO | | | SCAC4 |
| 41 | RSAY | ROUSELL-AYR-FARM | | | SCAC4 |
| 42 | RSB | Rubystar | Callsign: Rubystar, | BY | AVCODES |
| 43 | RSB | Regional Linhas Aereas S/A | Callsign: Aero Regional, | BR | AVCODES |
| 44 | RSB | Rubystar | | | ICAO1 |
| 45 | RSB | Rochester Subway | 1/1980-7/2005 | | NAKINA |
| 46 | RSB | Rochester Subway | 1/80-7/2000 | | NRHS |
| 47 | RSB | Rail Service Bremen GmbH | Bremen | D | privat-bahn.de |
| 48 | RSB | ROCHESTER SUBWAY | | | PWRC |
| 49 | RSB | Rochester Subway | | | RSRV |
| 50 | RSBA | ROAD SCHOLAR TRANSPORTATION LLC | | | SCAC4 |
| 51 | RSBC | RUSTMAN BUS COMPANY | | | SCAC3 |
| 52 | RSBC | ROSENBALM & SONS INC | | | SCAC4 |
| 53 | RSBG | ROSBOROUGH BOATS | | | SCAC4 |
| 54 | RSBG | Rennsteigbahn | | DE | VKM |
| 55 | RSBH | R S TRUCKING | | | SCAC4 |
| 56 | RSBI | RSB LOGISTIC INC | | | SCAC4 |
| 57 | RSBJ | ROXANA SPECIALIZED HAULERS INC | | | SCAC4 |
| 58 | RSBL | RONNIE S STANDARD BRED LTD | | | SCAC3 |
| 59 | RSBL | RSB Logistic | | D | TRAFFIC |
| 60 | RSBM | ROYAL SEED TRANSPORT | | | SCAC4 |
| 61 | RSBO | ROSSITER BOATS | | | SCAC4 |
| 62 | RSBP | ROSS, B T TRANSPORT | | | SCAC3 |
| 63 | RSBQ | ROYAL SILK ARTS | | | SCAC4 |
| 64 | RSBS | ROSEBURG TRANSFER & STORAGE INC | | | SCAC3 |
| 65 | RSBS | RSB FREIGHT SOLUTIONS LLC | | | SCAC4 |
| 66 | RSBT | R S B TRUCK RENTAL | | | SCAC3 |
| 67 | RSBU | RSB LOGISTIC PROJEKSPEDITION GMBH | | D | BIC |
| 68 | RSBV | R & S BULK SERVICE | | | SCAC4 |
| 69 | RSBY | RESPASS BEAUTY SUPPLY CO INC | | | SCAC3 |
| 70 | RSBY | RODGERS, BRIAN | | | SCAC4 |
| 71 | RSC | Aerolineas Ejecutivas Tarascas S.A. de C.V. | Callsign: Tarascas, | MEX | AVCODES |
| 72 | RSC | Canarias Airlines Compañía de Aviación, S.L. | Callsign: Canair, Founded in 2011. Commenced operations on 20 September 2011. Flights operated for Binter Canarias using IATA designator NT. | E | AVCODES |
| 73 | RSC | Aerolineas Ejecutivas Tarascas | | | ICAO1 |
| 74 | RSC | DB Schenker Rail Scandinavia A/S | 2009 - | DK | jernbanen.dk |
| 75 | RSC | DB Schenker Rail Scandinavia A/S | 2009 - | DK | TRAFFIC |
| 76 | RSC | DB Schenker Rail Scandinavia A/S | | DK | VKM |
| 77 | RSCA | ROAD SCHOLAR TRANSPORT, INC | | | SCAC3 |
| 78 | RSCA | ROAD SCHOLAR TRANSPORT INC | | | SCAC4 |
| 79 | RSCB | R STREET-CITY TRANSPORT LTD | | | SCAC4 |
| 80 | RSCG | R & S CARTAGE INC | | | SCAC3 |
| 81 | RSCH | ROSS CHARTERS INC, A NORTH CAROLINA | | | SCAC3 |
| 82 | RSCI | ROSECO INC | | | SCAC4 |
| 83 | RSCJ | RICHMOND STEEL CANADA LIMITED | | | SCAC4 |
| 84 | RSCK | R & S TRUCKING | | | SCAC3 |
| 85 | RSCK | RUSH CREEK TRUCKING LLC | | | SCAC4 |
| 86 | RSCL | ROTARY SHIPPING CO LIMITED | | | SCAC3 |
| 87 | RSCM | REPORT SHIPPING COMPANY LTD. | | | SCAC3 |
| 88 | RSCN | RSC TRANSPORTATION INC | | | SCAC4 |
| 89 | RSCO | RONS SERVICE CO | | | SCAC3 |
| 90 | RSCO | Rolling Stock Company | | RO | TRAFFIC |
| 91 | RSCO | ROLLING STOCK COMPANY S.A. | | RO | VKM |
| 92 | RSCQ | REIS CARTAGE CO | | | SCAC3 |
| 93 | RSCR | RUSCO TRUCKING | | | SCAC3 |
| 94 | RSCR | R S CARRIER INC | | | SCAC4 |
| 95 | RSCS | R & S COURIERS INC | | | SCAC3 |
| 96 | RSCT | RSC LOGISTICS LLC | | | SCAC4 |
| 97 | RSCU | RAMSEY SCARLETT & CO INC | | | SCAC3 |
| 98 | RSCU | RED SEA NAVIGATION CO | | | SCAC4 |
| 99 | RSCV | ROMAR STONE CARVING | | | SCAC4 |
| 100 | RSCX | Republic Steel Corp. | 7/1935-4/1970; eliminated 1/1972 | | NAKINA |
