| 1 | DE | Condor Flugdienst GmbH | ICAO: CFG, Callsign: Condor, IATA Prefix: 881, IATA designator changed from DF | D | AVCODES |
| 2 | DE | Delta Air Transport (D.A.T.) | ICAO: DAT, Callsign: Deltair, IATA designator changed to QG | B | AVCODES |
| 3 | DE | Dortmunder Eisenbahn GmbH | Dortmund | D | privat-bahn.de |
| 4 | DE | DETROIT EDISON COMPANY | | | PWRC |
| 5 | DE | Dortmunder Eisenbahn | | D | TRAFFIC |
| 6 | DE | Dortmunder Eisenbahn | | DE | VKM |
| 7 | DEA | Delta Aerotaxi | Callsign: Jet Service, | I | AVCODES |
| 8 | DEA | Delta Aerotaxi | | | ICAO1 |
| 9 | DEA | DELTA BUS LINES INC | | | SCAC4 |
| 10 | DEAA | DELUXE AUTO CARRIERS INC | | | SCAC4 |
| 11 | DEAB | DIRECT EXPRESS COURIER INC | | | SCAC4 |
| 12 | DEAC | DEBRITO TRANSPORTATION INC | | | SCAC4 |
| 13 | DEAE | DEBNER TRANSPORT INC | | | SCAC4 |
| 14 | DEAG | Dürener Eisenbahn AG | City: Düren | D | TRAFFIC |
| 15 | DEAN | DEANDA TRUCKING | | | SCAC4 |
| 16 | DEAO | DENIAL ART | | | SCAC4 |
| 17 | DEAT | DENA TRANSPORT | | | SCAC4 |
| 18 | DEAU | JSC ECOMET-S | | RUS | BIC |
| 19 | DEAU | JSC E3COMET-S | | | SCAC4 |
| 20 | DEAW | D & S EXPRESS DELIVERY | | | SCAC4 |
| 21 | DEAX | DEACERO S A DE C V | | | SCAC4 |
| 22 | DEAY | DEAL TRANSPORTATION INC | | | SCAC4 |
| 23 | DEB | Debonair Airways Ltd. | IATA: 2G, Callsign: Debonair, Ceased operations. Designator 2G reinsgtated by IATA | GB | AVCODES |
| 24 | DEB | Debonair | | GB | TRAFFIC |
| 25 | DEBD | DENISON, DONALD B | | | SCAC4 |
| 26 | DEBE | DEBOER TRANSPORT LLC | | | SCAC4 |
| 27 | DEBG | DEUTSCH TRUCKING | | | SCAC4 |
| 28 | DEBG | Dampfzug-Betriebs-Gemeinschaft e.V | | DE | VKM |
| 29 | DEBI | DERENIA ENTERPRISES INC | | | SCAC4 |
| 30 | DEBJ | DEVAL DENIZCILIK VE TICARET AS | | | SCAC4 |
| 31 | DEBK | DEBKO INC | | | SCAC4 |
| 32 | DEBL | DEL TRANSIT LLC | | | SCAC4 |
| 33 | DEBN | DE LOS SANTOS TRUCKING | | | SCAC4 |
| 34 | DEBP | DICKERSON TRANSPORTATION INC | | | SCAC4 |
| 35 | DEBQ | DOUBLE EAGLE BULK CARRIERS INC | | | SCAC4 |
| 36 | DEBU | NASACO INTERNATIONAL LIMITED | | CH | BIC |
| 37 | DEBU | NASACO INTERNL LIMITED | | | SCAC4 |
| 38 | DEBV | DRAGON ENTERPRISES LTD MARSHALL ISL | | | SCAC4 |
| 39 | DEBX | Ceres AG Products | 7/2005 (not listed) | | NAKINA |
| 40 | DEBX | CERES AG PRODUCTS | | | PWRC |
| 41 | DEBX | Ceres AG Products | | | RSRV |
| 42 | DEBZ | DEBOERS TRANSPORTATION INC | | | SCAC4 |
| 43 | DEC | Deltacraft Oy | IATA: 4L, Callsign: Deltacraft, Designator 4L* recalled by IATA | FIN | AVCODES |
| 44 | DEC | Deccan Cargo & Express Logistics Pvt Ltd | IATA: 3C, Callsign: Deccan Cargo, IATA Prefix: 360, | IND | AVCODES |
| 45 | DECAMP | Decamp Bus Lines | | USA | TRAFFIC |
| 46 | DECB | DEUTSCH ENGINEERED CONNECTING DEVIC | | | SCAC4 |
| 47 | DECD | DEC TRANSPORT INC | | | SCAC4 |
| 48 | DECJ | DE CARO TRUCKING CO INC | | | SCAC4 |
| 49 | DECM | DEL-CO SYSTEMS | | | SCAC4 |
| 50 | DECP | DIRECT EXPEDITED CORP | | | SCAC4 |
| 51 | DECR | DECOR N W INC | | | SCAC4 |
| 52 | DECT | DEC TRUCKING | | | SCAC4 |
| 53 | DECU | DECCAN FINE CHEMICALS INDIA PRIVATE LIMITED | | IND | BIC |
| 54 | DECX | Duval Engineering & Contracting Co. | 4/1947-10/1957; eliminated 4/1960 | | NAKINA |
| 55 | DECX | Duval Engineering & Contracting Co. | 1/52-10/57 | | NRHS |
| 56 | DECX | DUVAL ENGINEERING & CONTRACTING CO. | | | PWRC |
| 57 | DECZ | DECKER COAL CO. | | | PWRC |
| 58 | DECZ | DIRECT CHASSIS & EQUIPMENT | | | SCAC4 |
| 59 | DEDA | DEDICATED CARRIERS INC | | | SCAC4 |
| 60 | DEDD | DEDICATED TRANSPORTATION LLC | | | SCAC4 |
| 61 | DEDE | DEDICATED TRANSPORT SERVICES INC | | | SCAC4 |
| 62 | DEDG | DEDICATED TRUCKING INC | | | SCAC4 |
| 63 | DEDI | DEDICATED TRANSPORT LLC | | | SCAC4 |
| 64 | DEDK | DOVE MARINE CO LTD | | | SCAC4 |
| 65 | DEDL | DEDOLA GLOBAL LOGISTICS INC | | | SCAC4 |
| 66 | DEDO | DUENAS TRUCKING | | | SCAC4 |
| 67 | DEDR | DEPENDABLE DISTRIBUTION SERVICES IN | | | SCAC4 |
| 68 | DEDS | DEDICATED EXPRESS LLC | | | SCAC4 |
| 69 | DEDT | DEDICATED EXPRESS LOGISTICS | | | SCAC4 |
| 70 | DEDY | DIRECT EXPRESS DELIVERY INC | | | SCAC4 |
| 71 | DEE | Transportation America Corporation d/b/a Dixie Airways | Callsign: Tacair, Name changed from Dixie Airways | USA | AVCODES |
| 72 | DEE | Dixie Airways | Callsign: Dixair, Name changed to Transportation America Corporation d/b/a Dixie Airways | USA | AVCODES |
| 73 | DEE | Dixie Airways | | | ICAO1 |
| 74 | DEEA | DEEPSEA AGENCY LTD | | | SCAC4 |
| 75 | DEEF | DEER CREEK FARMS | | | SCAC4 |
| 76 | DEEL | DEN-EL TRANSFER CO INC | | | SCAC4 |
| 77 | DEEM | DEES MARINE AND POWERSPORTS | | | SCAC4 |
| 78 | DEEP | DEEP EXPRESS | | | SCAC4 |
| 79 | DEES | DEDIC8ED EXPRESS LLC | | | SCAC4 |
| 80 | DEEX | The Detroit Edison Co. | added 10/1968; 4/1970-7/2005 | | NAKINA |
| 81 | DEEX | The Detroit Edison Co. | added 10/68; 4/70-7/2000 | | NRHS |
| 82 | DEEX | DETROIT EDISON COMPANY | | | PWRC |
| 83 | DEEX | Detroit Edison | | | RSRV |
| 84 | DEEX | DETROIT EDISON COMPANY | | | SCAC4 |
| 85 | DEEX | The Detroit Edison Co. | | USA | TRAFFIC |
| 86 | DEF | Aviation Defense Service | Callsign: Tirpa, | F | AVCODES |
| 87 | DEF | Aviation Defense Service | | | ICAO1 |
| 88 | DEFA | DEFFEBACH, IAN | | | SCAC4 |
| 89 | DEFC | DELFIC GRACE SHIPPING LIMITED | | | SCAC4 |
| 90 | DEFV | DELUXE FREIGHT SERVICES LTD | | | SCAC4 |
| 91 | DEG | Air Service Groningen | | | ICAO1 |
| 92 | DEGD | DEGRAND, JOHN & SON INC | | | SCAC4 |
| 93 | DEGL | DEGOL AVIATION | | | SCAC4 |
| 94 | DEGR | DeGROOT MOTOR SERVICE, INC | | | SCAC1 |
| 95 | DEGS | DEGENSTEIN TRUCKING CO | | | SCAC4 |
| 96 | DEGUS | Degussa AG | | DE | VKM |
| 97 | DEGX | Mississippi Power Co. | added 7/1978; 1/1980-7/2005 | | NAKINA |
| 98 | DEGX | Mississippi Power Co. | added 7/78; 1/80-7/2000 | | NRHS |
| 99 | DEGX | MISSISSIPPI POWER COMPANY | | | PWRC |
| 100 | DEGX | Mississippi Power | | | RSRV |
