| 8201 | RRWX | THE SOUTH CAROLINA RAILROAD MUSEUM | | | SCAC4 |
| 8202 | RRXB | R & R TRANSPORT LLC | | | SCAC4 |
| 8203 | RRXC | RED ROSE TRANSPORTATION INC | | | SCAC4 |
| 8204 | RRXE | R&R EXPRESS | | | SCAC3 |
| 8205 | RRXE | R & R EXPRESS | | | SCAC4 |
| 8206 | RRXI | RAMAR TRANSPORTATION INC | | | SCAC4 |
| 8207 | RRXM | R & R TRANSPORTATION | | | SCAC4 |
| 8208 | RRXN | R & R EXPRESS INC | | | SCAC4 |
| 8209 | RRXP | ROAD RUNNER PACKAGE EXPRESS | | | SCAC3 |
| 8210 | RRXP | RIVERRUN EXPRESS INC | | | SCAC4 |
| 8211 | RRXQ | ROMIR EXPRESS INC | | | SCAC4 |
| 8212 | RRXS | R & R EXPRESS | | | SCAC4 |
| 8213 | RRXT | RREX TRUCKING INC | | | SCAC4 |
| 8214 | RRXU | PETIT FORESTIER CONTAINER NEDERLAND BV | | NL | BIC |
| 8215 | RRXU | REFTRADE RENTAL B V | | | SCAC4 |
| 8216 | RRY | R B Airline UK Ltd/Aviana Airways Ltd operating as Royal Bengal Airlines | IATA: 4A, Callsign: Royal Bengal, Founded in 2006. Commenced commercial operations on 31 January 2008. | BD | AVCODES |
| 8217 | RRY | Tbilisi Aviation University | | | ICAO1 |
| 8218 | RRYP | REY REY PRODUCE INC | | | SCAC4 |
| 8219 | RRYS | RIGEL REEDEREI GMBH & CO KG MT | | | SCAC4 |
| 8220 | RRYT | ROAD READY TRUCKING CO | | | SCAC3 |
| 8221 | RRZ | Rollright Aviation Ltd. | Callsign: Rollright, | GB | AVCODES |
| 8222 | RRZ | Rollright Aviation | | | ICAO1 |
| 8223 | RRZR | RAMOS RODRIGUEZ, RICARDO GUADALUPE | | | SCAC4 |
| 8224 | RS | Royal Flight of Oman | ICAO: ORF, Callsign: Oman, Name change to Oman Royal Flight. | OM | AVCODES |
| 8225 | RS | Aerofreight Airlines, JSC | ICAO: FRT, Callsign: Aerofreight, | RUS | AVCODES |
| 8226 | RS | Aerotransportes Entre Rios Srl | ICAO: SFA, Callsign: Aersa, Designator RS recalled by IATA | RA | AVCODES |
| 8227 | RS | Sky Regional Airlines, Inc. | ICAO: SKV, Callsign: Sky Regional, IATA Designator changed to KV. | CDN | AVCODES |
| 8228 | RS | Oman Royal Flight | ICAO: ORF, Callsign: Oman, Name change from Royal Flight of Oman. | OM | AVCODES |
| 8229 | RS | Air Seoul, Inc. | ICAO: ASV, Callsign: Air Seoul, | ROK | AVCODES |
| 8230 | RS | Roberval and Saguenay Ry. Co. | 10/1966 & 1/1975-7/2005; eliminated 1/2008 | | NAKINA |
| 8231 | RS | Roberval-Saguenay Ry. | 1/1941-4/1970 | | NAKINA |
| 8232 | RS | Roberval and Saguenay Ry. Co. | 4/1938 | | NAKINA |
| 8233 | RS | Roberval and Saguenay Ry. Co. | Apr-38 | | NRHS |
| 8234 | RS | Roberval-Saguenay Ry. | 1/52-4/70 | | NRHS |
| 8235 | RS | Roberval and Saguenay Ry. Co. | 10/66 & 1/75-7/2000 | | NRHS |
| 8236 | RS | ROBERVAL & SAGUENAY RAILWAY COMPANY | | | PWRC |
| 8237 | RS | Roberval and Saguenay Railway | | | RSRV |
| 8238 | RS | Roberval and Saguenay Ry. Co. | | USA | TRAFFIC |
| 8239 | RS | RS Railspeed SA | | CH | VKM |
| 8240 | RS&P | Roscoe, Snyder & Pacific Ry. | 7/1923-4/1938 | | NAKINA |
| 8241 | RS&P | Roscoe, Snyder & Pacific Ry. | Apr-38 | | NRHS |
| 8242 | RS&P | ROSCOE, SNYDER & PACIFIC RWY. | | | PWRC |
| 8243 | RSA | Elisra Airlines | Callsign: Esra, | SUD | AVCODES |
| 8244 | RSA | Air Service Affaires | | F | AVCODES |
| 8245 | RSA | Elisra Airlines | | | ICAO1 |
| 8246 | RSA | REPUBLIC STEEL CO.(ALABAMA) | | | PWRC |
| 8247 | RSA | Boliden Mineral AB | | SE | VKM |
| 8248 | RSAA | RHINO SPECIALIZED TRANSPORT LLC | | | SCAC4 |
| 8249 | RSAC | RAMSAY SCARLETT & CO INC | | | SCAC3 |
| 8250 | RSAC | R S TRANSPORT | | | SCAC4 |
| 8251 | RSAE | RSA EXPRESS INC | | | SCAC3 |
| 8252 | RSAE | RELIANT TRUCK LINES | | | SCAC4 |
| 8253 | RSAG | ROSE AGRI-SEED INC | | | SCAC4 |
| 8254 | RSAG | | City: Rostock | D | TRAFFIC |
| 8255 | RSAH | RSA LOGISTICS LLC | | | SCAC4 |
| 8256 | RSAI | RESAL INC | | | SCAC3 |
| 8257 | RSAM | ROSS, A M ENTERPRISES LTD | | | SCAC4 |
| 8258 | RSAO | RAMOS ACOSTA, AYDE | | | SCAC4 |
| 8259 | RSAQ | RUBBER SHIPPERS ASSOCIATION INC | | | SCAC3 |
| 8260 | RSAR | R S AIR SERVICES | | | SCAC4 |
| 8261 | RSAS | ROSAS TRANSPORTADORA S A DE C V | | | SCAC4 |
| 8262 | RSAT | R & S AUTO TRANSPORT | | | SCAC3 |
| 8263 | RSAT | REYES SANTOS, ARTEMIO | | | SCAC4 |
| 8264 | RSAY | ROUSELL-AYR-FARM | | | SCAC4 |
| 8265 | RSB | Rubystar | Callsign: Rubystar, | BY | AVCODES |
| 8266 | RSB | Regional Linhas Aereas S/A | Callsign: Aero Regional, | BR | AVCODES |
| 8267 | RSB | Rubystar | | | ICAO1 |
| 8268 | RSB | Rochester Subway | 1/1980-7/2005 | | NAKINA |
| 8269 | RSB | Rochester Subway | 1/80-7/2000 | | NRHS |
| 8270 | RSB | Rail Service Bremen GmbH | Bremen | D | privat-bahn.de |
| 8271 | RSB | ROCHESTER SUBWAY | | | PWRC |
| 8272 | RSB | Rochester Subway | | | RSRV |
| 8273 | RSBA | ROAD SCHOLAR TRANSPORTATION LLC | | | SCAC4 |
| 8274 | RSBC | RUSTMAN BUS COMPANY | | | SCAC3 |
| 8275 | RSBC | ROSENBALM & SONS INC | | | SCAC4 |
| 8276 | RSBG | ROSBOROUGH BOATS | | | SCAC4 |
| 8277 | RSBG | Rennsteigbahn | | DE | VKM |
| 8278 | RSBH | R S TRUCKING | | | SCAC4 |
| 8279 | RSBI | RSB LOGISTIC INC | | | SCAC4 |
| 8280 | RSBJ | ROXANA SPECIALIZED HAULERS INC | | | SCAC4 |
| 8281 | RSBL | RONNIE S STANDARD BRED LTD | | | SCAC3 |
| 8282 | RSBL | RSB Logistic | | D | TRAFFIC |
| 8283 | RSBM | ROYAL SEED TRANSPORT | | | SCAC4 |
| 8284 | RSBO | ROSSITER BOATS | | | SCAC4 |
| 8285 | RSBP | ROSS, B T TRANSPORT | | | SCAC3 |
| 8286 | RSBQ | ROYAL SILK ARTS | | | SCAC4 |
| 8287 | RSBS | ROSEBURG TRANSFER & STORAGE INC | | | SCAC3 |
| 8288 | RSBS | RSB FREIGHT SOLUTIONS LLC | | | SCAC4 |
| 8289 | RSBT | R S B TRUCK RENTAL | | | SCAC3 |
| 8290 | RSBU | RSB LOGISTIC PROJEKSPEDITION GMBH | | D | BIC |
| 8291 | RSBV | R & S BULK SERVICE | | | SCAC4 |
| 8292 | RSBY | RESPASS BEAUTY SUPPLY CO INC | | | SCAC3 |
| 8293 | RSBY | RODGERS, BRIAN | | | SCAC4 |
| 8294 | RSC | Aerolineas Ejecutivas Tarascas S.A. de C.V. | Callsign: Tarascas, | MEX | AVCODES |
| 8295 | RSC | Canarias Airlines Compañía de Aviación, S.L. | Callsign: Canair, Founded in 2011. Commenced operations on 20 September 2011. Flights operated for Binter Canarias using IATA designator NT. | E | AVCODES |
| 8296 | RSC | Aerolineas Ejecutivas Tarascas | | | ICAO1 |
| 8297 | RSC | DB Schenker Rail Scandinavia A/S | 2009 - | DK | jernbanen.dk |
| 8298 | RSC | DB Schenker Rail Scandinavia A/S | 2009 - | DK | TRAFFIC |
| 8299 | RSC | DB Schenker Rail Scandinavia A/S | | DK | VKM |
| 8300 | RSCA | ROAD SCHOLAR TRANSPORT, INC | | | SCAC3 |
