| 2601 | SDY | Island Express | IATA: 2S | | ICAO1 |
| 2602 | SDYA | SHADY MAPLE TRUCKING INC | | | SCAC4 |
| 2603 | SDYB | STAT DELIVERY LLC | | | SCAC4 |
| 2604 | SDYC | SUDDATH RELOCATION SYSTEMS OF CHARL | | | SCAC4 |
| 2605 | SDYE | SAME DAY EXPRESS CARTAGE LLC | | | SCAC4 |
| 2606 | SDYF | SUNSET DELIVERY SERVICE INC | | | SCAC4 |
| 2607 | SDYG | SAME DAY AIR GLOBAL INC | | | SCAC4 |
| 2608 | SDYH | SUNDAY, THOMAS C INC | | | SCAC4 |
| 2609 | SDYI | STEWART DELIVERY SERVICE INC | | | SCAC4 |
| 2610 | SDYL | SIDDOWAY, LANCE | | | SCAC4 |
| 2611 | SDYM | STATRANS DELIVERY SYSTEM INC | | | SCAC4 |
| 2612 | SDYN | SABOU DYNAMIC INC | | | SCAC4 |
| 2613 | SDYO | STURDY OIL CO | | | SCAC4 |
| 2614 | SDYP | SAME DAY AIR CORP | | | SCAC4 |
| 2615 | SDYQ | STARBOARD TRADING COMPANY INC | | | SCAC4 |
| 2616 | SDYS | STEWART DELIVERY SERVICE INCORPORAT | | | SCAC4 |
| 2617 | SDYT | SMITHS DAIRY TRUCKING COMPANY | | | SCAC4 |
| 2618 | SDZ | Sudan Pezetel For Aviation | Callsign: Sudana, | SUD | AVCODES |
| 2619 | SDZ | Sudan Pezetel for Aviation | | | ICAO1 |
| 2620 | SDZC | SONORA DEISTRIBUITING LLC | | | SCAC4 |
| 2621 | SDZK | SANDEZ TRUCKING | | | SCAC4 |
| 2622 | SDZM | SHEPARD MOTOR LINES INC | | | SCAC4 |
| 2623 | SDZP | SDL ENTERPRISES | | | SCAC4 |
| 2624 | SE | Samoa Aviation, Inc. | | ASM | AVCODES |
| 2625 | SE | Wings of Alaska | IATA designator changed to K5 | USA | AVCODES |
| 2626 | SE | Dairo Air Services Ltd. | ICAO: DSR, Callsign: Dairair, Designator SE* recalled by IATA | EAU | AVCODES |
| 2627 | SE | Aerolineas Flecha Austral Ltda. (ALFA) | Callsign: Alfa, | RCH | AVCODES |
| 2628 | SE | STAR Airlines | ICAO: SEU, Callsign: Starway, Name changed to XL Ariways France. Name changed from STAR Europe (Societe de Transport Aerien Regional) IATA Designator changed from 2R | F | AVCODES |
| 2629 | SE | British Charter | ICAO: BCR, Callsign: Sierra Echo, Designator SE recalled by IATA. ICAO callsign changed to Backer. | GB | AVCODES |
| 2630 | SE | XL Airways France | ICAO: XLF, Callsign: Starway, IATA Prefix: 473, Name changed from STAR Airlines. ICAO designator changed from SEU. Name changed from STAR Europe (Societe de Transport Aerien Regional) IATA Designator changed from 2R | F | AVCODES |
| 2631 | SE | XL Airways France | ICAO: XLF, Callsign: Starway, IATA Prefix: 473, Ceased operations on 30 September 2019. Name changed from STAR Airlines. ICAO designator changed from SEU. Name changed from STAR Europe (Societe de Transport Aerien Regional) IATA Designator changed from 2R | F | AVCODES |
| 2632 | SE | Holland Aero Leasing B.V. | ICAO: HAO, Callsign: Tulip, ICAO callsign changed from Aerolines. | NL | AVCODES |
| 2633 | SE | European Cargo Limited | ICAO: URO, Callsign: Euro, IATA Prefix: 436, IATA designator changed from PS*. | GB | AVCODES |
| 2634 | SE | Ferrocarrils Unidos del Sureste, S.A. de C.V. | 1/1975-1/1980 | | NAKINA |
| 2635 | SE | Semo Port R.R., Inc. | added 1/1995; 7/2000-7/2005 | | NAKINA |
| 2636 | SE | Ferrocarrils Unidos del Sureste, S.A. de C.V. | 1/75-1/80 | | NRHS |
| 2637 | SE | Semo Port R.R., Inc. | added 1/95; 7/2000 | | NRHS |
| 2638 | SE | *FERROCARRILES UNIDOS DEL SURESTE | | | PWRC |
| 2639 | SE | +SEMO PORT RAILROAD INCORPORATED | | | PWRC |
| 2640 | SE | Ferrocarriles Unidos del Sureste | | | RSRV |
| 2641 | SE | SEMO PORT RAILROAD INC | | | SCAC4 |
| 2642 | SE | Société Générale des chemins de fer économique | | F | TRAFFIC |
| 2643 | SE | Förderverein Steigerwald-Express e.V | | DE | VKM |
| 2644 | SE&W | The St. Louis, El Reno and Western Ry. Co. | 7/1923 | | NAKINA |
| 2645 | SE&W | ST. LOUIS, EL RENO & WESTERN RWY. CO. | | | PWRC |
| 2646 | SEA | Southeast Air, Inc. | Callsign: Southwest Air, | USA | AVCODES |
| 2647 | SEA | Southeast Air | | | ICAO1 |
| 2648 | SEA | SEASHORE TRANSPORTATION CO INC | | | SCAC4 |
| 2649 | SEA | Service des Essences des Armées | | FR | VKM |
| 2650 | SEAA | SEA ENTERPRISES | | | SCAC4 |
| 2651 | SEAB | Seaboard System | | USA | TRAFFIC |
| 2652 | SEAC | SEALAND SERVICE, INC. | | | PWRC |
| 2653 | SEAC | SEA-COLD SERVICE, INC | | | SCAC4 |
| 2654 | SEAE | SEAPORT EXPRESS TRANSPORT INC | | | SCAC4 |
| 2655 | SEAF | SEAWAY FUELS TRUCKING INC | | | SCAC4 |
| 2656 | SEAG | SEAGATE LOGISTICS INC | | | SCAC4 |
| 2657 | SEAG | Schweizer Electronic AG | | CH | VKM |
| 2658 | SEAH | SEAHORSE TRANSPORT INC | | | SCAC4 |
| 2659 | SEAI | S E A CORP | | | SCAC4 |
| 2660 | SEAL | SEALAND INDUSTRIES LTD | | | SCAC4 |
| 2661 | SEAM | SEAMAR CONT SHIPPING INC NJ | | | SCAC4 |
| 2662 | SEAN | SEACON | | | SCAC4 |
| 2663 | SEANT | SEANTO, S.L. | | ES | VKM |
| 2664 | SEAO | SEA ISLAND BONDED STORAGE OF GA INC | | | SCAC4 |
| 2665 | SEAP | SEATAINER TRANSPORT LP | | | SCAC4 |
| 2666 | SEAQ | SEA TANKERS SHIPPING INC | | | SCAC4 |
| 2667 | SEAR | SEAROSE MARINE SA | | | SCAC4 |
| 2668 | SEARL | SEA-RAIL NV | | BE | VKM |
| 2669 | SEAS | SEASTAR MARINE SA | | | SCAC4 |
| 2670 | SEAS | Slovenské elektrárne a.s. | | SK | VKM |
| 2671 | SEATD | Southeast Area Transit | SEAT’s member towns are: East Lyme, Griswold, Groton, Lisbon, Montville, New London, Norwich, Stonington and Waterford. | USA | TRAFFIC |
| 2672 | SEAU | MAERSK A/S | | DK | BIC |
| 2673 | SEAU | SEALAND SERVICE INC | | | PWRC |
| 2674 | SEAU | Sea-Land Service Inc | | | RSRV |
| 2675 | SEAU | SEA-LAND SERVICE, INC | | | SCAC1 |
| 2676 | SEAU | A P MOLLER | | | SCAC4 |
| 2677 | SEAW | SEA WINGS USA | | | SCAC4 |
| 2678 | SEAX | Seahorse Fuels, Inc. | added 1/1962; 7/1965-4/1970; eliminated 7/1971 | | NAKINA |
| 2679 | SEAX | Seahorse Fuels, Inc. | added 1/62; 7/65-4/70 | | NRHS |
| 2680 | SEAX | SEAHOURSE FUELS, INC. | | | PWRC |
| 2681 | SEAY | SESA EXPRESS INC | | | SCAC4 |
| 2682 | SEB | Servicios Aereos Luce, S.A. de C.V. | Callsign: Serviluce, | MEX | AVCODES |
| 2683 | SEB | Servicios Aereos Luce | | | ICAO1 |
| 2684 | SEB | Strausberger Eisenbahn GmbH | Real: STE, City: Strausberg | D | TRAFFIC |
| 2685 | SEBA | SEBAGO ENERGY CO | | | SCAC4 |
| 2686 | SEBD | SEABOARD INTERNATIONAL SHIPPING CO | | | SCAC4 |
| 2687 | SEBF | SEALINK INTERNATIONAL INC | | | SCAC4 |
| 2688 | SEBJ | SHOWBOUND EXPRESS INC | | | SCAC4 |
| 2689 | SEBN | SPRINGER-EUBA | | | SCAC4 |
| 2690 | SEBO | SEBERT OIL INC | | | SCAC4 |
| 2691 | SEBQ | SEWARD GROUP, THE | | | SCAC4 |
| 2692 | SEBT | SEABOATS INC | | | SCAC4 |
| 2693 | SEBU | ACTIVE CONTAINERS SERVICES BV | | NL | BIC |
| 2694 | SEBUC | SUCURSALA ELECTROCENTRALE BUCURESTI | | RO | VKM |
| 2695 | SEC | South East College Of Air Training | Callsign: Secoat, | GB | AVCODES |
| 2696 | SEC | 3D Aviation | | | ICAO1 |
| 2697 | SECD | SEC SAWMILL EQUIPMENT COMPANY INC | | | SCAC4 |
| 2698 | SECE | SEACOAST TRUCKING INC | | | SCAC4 |
| 2699 | SECG | SILVER EAGLE CO | | | PWRC |
| 2700 | SECG | SILVER EAGLE COMPANY | | | SCAC1 |
