| 4401 | AEX | The Andersons | | USA | TRAFFIC |
| 4402 | AEXA | ASSOCIATED EXPREES INC | | | SCAC4 |
| 4403 | AEXB | ADMIRAL EXPRESS | | | SCAC3 |
| 4404 | AEXB | ACE TRANSPORT | | | SCAC4 |
| 4405 | AEXC | ANZIO EXPRESS CO INC | | | SCAC3 |
| 4406 | AEXC | A-ONE (A-1) EXPRESS | | | SCAC4 |
| 4407 | AEXD | ACTION EXPEDITORS INC | | | SCAC3 |
| 4408 | AEXE | ACTION EXPRESS INC | | | SCAC3 |
| 4409 | AEXE | ALLIANCE EXPRESS LLC | | | SCAC4 |
| 4410 | AEXF | ANDERSON EXPRESS | | | SCAC3 |
| 4411 | AEXF | AUTO EXPRESS FRONTERA NORTE SA DE C | | | SCAC4 |
| 4412 | AEXG | AUTO EXPEDITING INC | | | SCAC3 |
| 4413 | AEXG | AUTO EXPEDITING INC | | | SCAC4 |
| 4414 | AEXH | AMERICAN EXHIBITION SERVICES INT'L. | | | SCAC3 |
| 4415 | AEXI | ARMSTRONG EXPEDITE INC | | | SCAC4 |
| 4416 | AEXL | AMBASSADOR EXPEDITORS LTD | | | SCAC3 |
| 4417 | AEXL | AB EXPEDITED LLC | | | SCAC4 |
| 4418 | AEXM | AD COM EXPRESS | | | SCAC3 |
| 4419 | AEXM | APEX BULK CARRIERS LLC | | | SCAC4 |
| 4420 | AEXN | ATLANTA EXCURSIONS INC | | | SCAC3 |
| 4421 | AEXN | ATLANTA EXCURSIONS INC | | | SCAC4 |
| 4422 | AEXO | A A A AIR EXPRESS INC | | | SCAC3 |
| 4423 | AEXO | AMTEX TRANSPORT | | | SCAC4 |
| 4424 | AEXP | ARLINGTON EXPRESS, INC | | | SCAC3 |
| 4425 | AEXP | ANGELES EXPRESS | | | SCAC4 |
| 4426 | AEXPA | Aero Expreso del Pacífico | Aexpa S.A. is a charter airline based at Matecaña International Airport in Pereira, Colombia | CO | TRAFFIC |
| 4427 | AEXQ | ALCO EXPRESS | | | SCAC3 |
| 4428 | AEXR | ABCO EXPRESS | | | SCAC3 |
| 4429 | AEXS | ALS EXPRESS (A DIV OF PAT ARTHURS T | | | SCAC3 |
| 4430 | AEXT | ABSOLUTE EXPRESS LLC | | | SCAC4 |
| 4431 | AEXU | AFRICA EXPRESS LINE LTD | | GB | BIC |
| 4432 | AEXW | AVILA EXPRESS | | | SCAC4 |
| 4433 | AEY | Aerolyon | IATA: 4Q, Callsign: Aerolyon, Name changed to L-Air | F | AVCODES |
| 4434 | AEY | Aerolyon | IATA: DD, IATA designator changed to 4Q | F | AVCODES |
| 4435 | AEY | L-Air Holdings | IATA: 4Q, Callsign: Aerolyon, Designator 4Q recalled by IATA. Name changed from Aerolyon | F | AVCODES |
| 4436 | AEY | L-Air Holdings | Callsign: Aerolyon, Airline Liquidqted by courts 26 December 2002. Designator 4Q recalled by IATA. Name changed from Aerolyon | F | AVCODES |
| 4437 | AEY | Air Italy S.p.A. | IATA: I9, Callsign: Air Italy, ICAO Designator changed from AJR. Designator I9* recalled by IATA. Designator NN recalled by IATA | I | AVCODES |
| 4438 | AEY | Air Italy S.p.A. | IATA: I9, Callsign: Air Italy, IATA Prefix: 067, Ceased operation on 11 February 2020. Name changed to Air Italy Fleet Management, S.p.A. w.e.f. 01 March 2018. AOC returned on 01 March 2018. ICAO Designator changed from AJR. Designator I9* reinstated by IATA. Designator NN recalled by IATA | I | AVCODES |
| 4439 | AEY | Air Italy S.p.A. | IATA: I9, Callsign: Air Italy, Merged into Meridiana fly on 18 July 2011. IATA Accounting code and Prefix code recalled. ICAO Designator changed from AJR. Designator I9* reinstated by IATA. Designator NN recalled by IATA | I | AVCODES |
| 4440 | AEY | Aeroservicios Centroamericanos S. de R.L. | Callsign: Zeus, | PA | AVCODES |
| 4441 | AEY | Air Italy | IATA: I9 | | ICAO1 |
| 4442 | AEYC | AGRICULTURE & ENERGY CARRIERS LTD | | | SCAC4 |
| 4443 | AEYI | AKAL ENERGY INC | | | SCAC4 |
| 4444 | AEYN | AEROUNION | | | SCAC4 |
| 4445 | AEZ | Aerial Transit Company | Callsign: Aerial Tranz, | USA | AVCODES |
| 4446 | AEZ | Aeroitalia S.r.l. | IATA: XZ, Callsign: Aeroitalia, | I | AVCODES |
| 4447 | AEZ | Aerial Transit Company | | | ICAO1 |
| 4448 | AEZ | AeroItalia | | I | TRAFFIC |
| 4449 | AEZS | ARMADORES ERMOINE S.A. | | | SCAC3 |
| 4450 | AEZT | AZTEC ENTERPRISE | | | SCAC4 |
| 4451 | AF | Air France | ICAO: AFR, Callsign: Airfrans, IATA Prefix: 057, | F | AVCODES |
| 4452 | AF | Alabama & Florida Ry. Co. | 1/1994-7/2005 | | NAKINA |
| 4453 | AF | Alabama & Florida Ry. Co. | 1/94-7/2000 | | NRHS |
| 4454 | AF | ALABAMA & FLORIDA RAILWAY, INC. | | | PWRC |
| 4455 | AF | Alabama and Florida Railway | | | RSRV |
| 4456 | AF | ALABAMA & FLORIDA RAILWAY CO | | | SCAC4 |
| 4457 | AF | Air France | | F | TRAFFIC |
| 4458 | AF | Albert Fischer GmbH | | DE | VKM |
| 4459 | AFA | Alfa Air s.r.o. | Callsign: Blue Alfa, | CZ | AVCODES |
| 4460 | AFA | Arcata Flying Service | Callsign: Arcata, | USA | AVCODES |
| 4461 | AFA | Alfa Air | | | ICAO1 |
| 4462 | AFA | Automobilverkehr Frutigen - Adelboden AG | | CH | TRAFFIC |
| 4463 | AFAA | ALFALFA + | | | SCAC3 |
| 4464 | AFAA | AF TRANSPORT | | | SCAC4 |
| 4465 | AFAB | AFRICA TANKER CORPORATION | | | SCAC4 |
| 4466 | AFAC | ALBRITTON FARMS | | | SCAC3 |
| 4467 | AFAC | ALBRITTON FARMS | | | SCAC4 |
| 4468 | AFAE | ALF | | | SCAC4 |
| 4469 | AFAF | AIR FREIGHT TRANSPORTATION CORP | | | SCAC3 |
| 4470 | AFAG | ADMIRAL TRANSFER AND RIGGING INC | | | SCAC4 |
| 4471 | AFAG | | City: Flensburg | D | TRAFFIC |
| 4472 | AFAH | AFFILIATED ARCHIVES INC | | | SCAC4 |
| 4473 | AFAI | ARRANGE FREIGHT LLC | | | SCAC4 |
| 4474 | AFAK | AMFAK | | | SCAC3 |
| 4475 | AFAK | AMFAK | | | SCAC4 |
| 4476 | AFAL | AIR FREIGHT ATLANTA | | | SCAC4 |
| 4477 | AFAO | ACE FREIGHT SERVICE INC | | | SCAC4 |
| 4478 | AFAQ | A FASTWAY | | | SCAC3 |
| 4479 | AFAQ | AFC OCEAN CARRIERS | | | SCAC4 |
| 4480 | AFAV | AIR FREIGHT ASSOCIATES OF ROANOKE I | | | SCAC3 |
| 4481 | AFAY | A C E FREIGHT AGENCY INC | | | SCAC3 |
| 4482 | AFAY | AMERICAN FREIGHT LOGISTICS INC | | | SCAC4 |
| 4483 | AFB | American Falcon, S.A. | IATA: WK, Callsign: American Falcon, IATA Prefix: 676, | RA | AVCODES |
| 4484 | AFB | Belgium Air Force | Callsign: Belgium Air Force, ICAO designator changed from AFB. Designator EB recalled by IATA. ICAO callsign changed from Bafair | B | AVCODES |
| 4485 | AFB | Belgium Air Force | IATA: EB, Callsign: Bafair, Designator EB recalled by IATA. ICAO callsign changed to Belgium Air Force | B | AVCODES |
| 4486 | AFB | Bulgarian Air Force | Callsign: Bulaf, | BG | AVCODES |
| 4487 | AFB | American Falcon | IATA: WK | | ICAO1 |
| 4488 | AFBB | ABBA FREIGHT SYSTEMS LLC | | | SCAC4 |
| 4489 | AFBC | AFI TRANSPORT INC | | | SCAC4 |
| 4490 | AFBE | AMERICAN FREIGHT LLC | | | SCAC4 |
| 4491 | AFBG | ALCARA FREIGHT BROKERAGE INC | | | SCAC3 |
| 4492 | AFBG | ACTION FIBERGLASS & MFG LTD | | | SCAC4 |
| 4493 | AFBH | AXESS FREIGHT TRANSPORT INC | | | SCAC4 |
| 4494 | AFBI | ALFAB, INC | | | SCAC3 |
| 4495 | AFBI | A-FAST DELIVERY | | | SCAC4 |
| 4496 | AFBK | AARON FREIGHT BROKERS | | | SCAC3 |
| 4497 | AFBK | ALFA TRUCKING INC | | | SCAC4 |
| 4498 | AFBL | AFRICAN BULK SERVICES INC. | | | SCAC3 |
| 4499 | AFBN | ADVANCE FREIGHT CARGO | | | SCAC4 |
| 4500 | AFBO | ADVENTURE FREIGHT BROKERS | | | SCAC4 |
