| 4601 | DRUM | DRUMMOND, HARRY W INC | | | SCAC4 |
| 4602 | DRUS | DARMAN RECYCLING USA INC | | | SCAC4 |
| 4603 | DRUS | Dardanelle & Russellville | Real: DR | USA | TRAFFIC |
| 4604 | DRUT | DANAS RUN TRANSPORT | | | SCAC4 |
| 4605 | DRVC | DHRUV TRANSPORT INC | | | SCAC4 |
| 4606 | DRVD | DOUBLE R VENDING INC | | | SCAC4 |
| 4607 | DRVE | DOWNRIVER LLC | | | SCAC4 |
| 4608 | DRVI | DRIVEN INC | | | SCAC4 |
| 4609 | DRVK | DORVAL TANKSHIPS PTY LTD | | | SCAC4 |
| 4610 | DRVL | DRIVERS LOGISTICS LTD | | | SCAC4 |
| 4611 | DRVM | DELGADO RIVERA, CARMEN | | | SCAC4 |
| 4612 | DRVO | DRIVE-ON TRANSPORT | | | SCAC4 |
| 4613 | DRVW | DRIVEAWAY USA INC | | | SCAC4 |
| 4614 | DRW | Dream Wind Airlines | Callsign: Dream Wind, AOC revoked by SAAU on 15 November 2019. | UA | AVCODES |
| 4615 | DRWC | DREW TRUCKING LLC | | | SCAC4 |
| 4616 | DRWD | DURAND, RONALD WALTER | | | SCAC4 |
| 4617 | DRWF | DARWIN FREIGHT SERVICES LLC | | | SCAC4 |
| 4618 | DRWH | DRW ENTERPRISES | | | SCAC4 |
| 4619 | DRWI | Dampfbahn Ruhr Wurm Inde e.V. | Düren | D | privat-bahn.de |
| 4620 | DRWJ | DORNER, WAYLON J | | | SCAC4 |
| 4621 | DRWL | DAVIS, R W OIL CO INC | | | SCAC4 |
| 4622 | DRWO | DREW OIL COMPANY INC | | | SCAC4 |
| 4623 | DRWQ | D & R TOWING | | | SCAC4 |
| 4624 | DRWR | DREW CORPORATION | | | SCAC4 |
| 4625 | DRWS | DRW TRANSPORTATION LTD | | | SCAC4 |
| 4626 | DRWX | Drew Sales Co. | 1/1950 | | NAKINA |
| 4627 | DRWX | DREW SALES CO. | | | PWRC |
| 4628 | DRWY | Denver Ry., Inc. | added 1/1990; eliminated 10/1992; 1/1994 | | NAKINA |
| 4629 | DRWY | Denver Ry., Inc. | added 1/90; eliminated 10/92; 1/94 | | NRHS |
| 4630 | DRWY | RETIRED 11-8-93 ATP (244) {DENVER RAILWAY, INC.] | | | PWRC |
| 4631 | DRX | Des R. Cargo Express | | RIM | AVCODES |
| 4632 | DRX | Des R Cargo Express | | | ICAO1 |
| 4633 | DRX | Deep Rock Oil Corp. | 7/1930-1/1950 | | NAKINA |
| 4634 | DRX | Deep Rock Oil Corp. | Apr-38 | | NRHS |
| 4635 | DRX | DEEP ROCK OIL CORP. | | | PWRC |
| 4636 | DRX | Deep Rock Oil Corp. | | USA | TRAFFIC |
| 4637 | DRXC | DEVEREAUX, CHRIS | | | SCAC4 |
| 4638 | DRXI | DARAR TRANSPORT INC | | | SCAC4 |
| 4639 | DRXM | DIRECT TRANSPORT LLC | | | SCAC4 |
| 4640 | DRXQ | DART EXPRESS (LAX) INC | | | SCAC4 |
| 4641 | DRXR | DRAXLER TRANSPORT INC | | | SCAC4 |
| 4642 | DRXT | DEALER TRANSPORT INC | | | SCAC4 |
| 4643 | DRXUK | Drax Power Ltd. | | UK | VKM |
| 4644 | DRXW | DR EXPRESS LLC | | | SCAC4 |
| 4645 | DRXY | D & R TRANSPORT LLC | | | SCAC4 |
| 4646 | DRY | Deraya Air Taxi PT. | Callsign: Deraya, Name changed from Deraya P.T. | RI | AVCODES |
| 4647 | DRY | Deraya Air Taxi | | | ICAO1 |
| 4648 | DRYA | DRYAIR 2000 INC | | | SCAC4 |
| 4649 | DRYF | DRY CREEK FARMS INC | | | SCAC4 |
| 4650 | DRYG | DRAYAGE EXPRESS LLC | | | SCAC4 |
| 4651 | DRYM | READY MATERIALS TRANSPORT LLC | | | SCAC4 |
| 4652 | DRYN | DARYL FLOOD INC | | | SCAC4 |
| 4653 | DRYR | DRAY-CON TRANSPORT INC | | | SCAC4 |
| 4654 | DRYT | DRYTECH INTERNATIONAL INC | | | SCAC4 |
| 4655 | DRYU | SEACUBE CONTAINERS LLC | | USA | BIC |
| 4656 | DRYU | Seacube Container Leasing | | | RSRV |
| 4657 | DRYU | CARLISLE LEASING INTERNATIONAL | | | SCAC4 |
| 4658 | DRYX | Merchants Despatch Transportation Corp. | added 10/1960; 4/1961; eliminated 7/1962 | | NAKINA |
| 4659 | DRYX | Merchants Despatch Transportation Corp. | added 10/60; 4/61 | | NRHS |
| 4660 | DRYX | MERCHANTS DESPATCH TRANSPORTATION CORP. | | | PWRC |
| 4661 | DRZ | Derazona Air Service, PT. | Callsign: Derazona, | RI | AVCODES |
| 4662 | DRZO | DURAZO ROBLES, JOSE JESUS | | | SCAC4 |
| 4663 | DRZU | COVORO MINING SOLUTIONS | | USA | BIC |
| 4664 | DS | Easyjet Switzerland S.A. | ICAO: EZS, Callsign: Topswiss, IATA Designator BH* recalled. Name changed from TEA Basel AG | CH | AVCODES |
| 4665 | DS | DHL Aero Expreso, S.A. | ICAO: DAE, IATA designator changed to D5 | PA | AVCODES |
| 4666 | DS | Air Senegal, Société Nationale de Transport Aerien | ICAO: DSB, Callsign: Sonatra-Air Senegal, | SN | AVCODES |
| 4667 | DS | Compagnie Senegalaise de Transports Aériens | Callsign: Coseta, Name changed to Air Senegal, Societe Nationale de Transport Aerien | SN | AVCODES |
| 4668 | DS | DAS Nordisk Ltd. | Non-Airline Unit Load Devices (ULD) company | HK | AVCODES |
| 4669 | DS | Durham and Southern Ry. Co. | 1/1975-1/1980; eliminated 4/1982 | | NAKINA |
| 4670 | DS | Durham and Southern Ry. Co. | 1/75-1/80; eliminated 4/82 | | NRHS |
| 4671 | DS | DURHAM & SOUTHERN RAILWAY CO. | | | PWRC |
| 4672 | DS | Durango and Silverton Railroad | Real: DSNG | USA | TRAFFIC |
| 4673 | DS&A | Duluth, South Shore & Atlantic Ry. | 8/1920-7/1932 | | NAKINA |
| 4674 | DS&A | Duluth, South Shore & Atlantic Ry. | 23-Jul | | NRHS |
| 4675 | DS&A | DULUTH SOUTH SHORE & ATLANTIC RWY. | | | PWRC |
| 4676 | DSA | Danbury Airways, Inc. | Callsign: Danbury Airways, | USA | AVCODES |
| 4677 | DSA | Danbury Airways | | | ICAO1 |
| 4678 | DSA | Soo Line R.R. | eliminated 11/1973; 1/1975 & 1/1994-7/2005 | | NAKINA |
| 4679 | DSA | Duluth, South Shore and Atlantic R.R. Co. | 10/1966 | | NAKINA |
| 4680 | DSA | Soo Line R.R. | 7/1965 | | NAKINA |
| 4681 | DSA | Duluth, South Shore & Atlantic R.R. | 1/1943-1/1946; 1/1950-4/1961 | | NAKINA |
| 4682 | DSA | Duluth, South Shore & Atlantic Ry. | 1/1941 & 4/1947 | | NAKINA |
| 4683 | DSA | Duluth, South Shore & Atlantic R.R. | 1/52-4/61 | | NRHS |
| 4684 | DSA | Soo Line R.R. | Jul-65 | | NRHS |
| 4685 | DSA | Duluth, South Shore and Atlantic R.R. Co. | Oct-66 | | NRHS |
| 4686 | DSA | Soo Line R.R. | eliminated 11/73; 1/75 & 1/94-7/2000 | | NRHS |
| 4687 | DSA | CANADIAN PACIFIC RWY [SOO LINE RAILROAD] [DULUTH SOUTH SHORE & ATLANTIC RWY.] | | | PWRC |
| 4688 | DSA | Duluth, South Shore & Atlantic Railway (Canadian Pacific Railway) | | | RSRV |
| 4689 | DSA | Duluth, South Shore and Atlantic R.R. Co. | | USA | TRAFFIC |
| 4690 | DSAA | DSN LOGISTICS INC | | | SCAC4 |
| 4691 | DSAC | D & S RESOURCES LTD | | | SCAC4 |
| 4692 | DSAE | DEDICATED TRANSPORTATION SOLUTIONS | | | SCAC4 |
| 4693 | DSAF | DIAMOND S TRUCKING | | | SCAC4 |
| 4694 | DSAI | DAVIDSON SURFACE/AIR INC | | | SCAC4 |
| 4695 | DSAL | DISALVO TRUCKING CO | | | PWRC |
| 4696 | DSAL | Di SALVO TRUCKING CO | | | SCAC1 |
| 4697 | DSAM | DS EXPRESS CARRIERS INC | | | SCAC4 |
| 4698 | DSAN | DJ TRANSPORT LLC | | | SCAC4 |
| 4699 | DSAP | D & S TRANSPORTATION LLC | | | SCAC4 |
| 4700 | DSAS | DAVIS SHIP AGENCIES INC | | | SCAC4 |
