| 1 | DR | Mediterranean Air Service | | TN | AVCODES |
| 2 | DR | Air Link Pty Ltd. | | AUS | AVCODES |
| 3 | DR | Sociedade Brasileira de Turismo (ROTASTUR) | ICAO: RTR, Callsign: Delta Romeo, ICAO callsign changed to Rotatur | BR | AVCODES |
| 4 | DR | Avdev Airlines of Australia | | AUS | AVCODES |
| 5 | DR | Panair Luftverkehrsgesellschaft mbH & Co. | Callsign: Delta Romeo, | D | AVCODES |
| 6 | DR | Ruili Airlines Co., Ltd. | ICAO: RLH, Callsign: Sendi, Name changed to Sunan Ruili Airlines Co., Ltd. On 18 October 2021. | PRC | AVCODES |
| 7 | DR | Sunan Ruili Airlines Co., Ltd. | ICAO: RLH, Callsign: Sendi, Name changed from Ruili Airlines Co., Ltd. On 18 October 2021. | PRC | AVCODES |
| 8 | DR | Dardanelle & Russellville R.R. Co. | 1/1975-1/1980; added 7/1981; eliminated 7/1988; 1/1994-7/2005 | | NAKINA |
| 9 | DR | Dardanelle & Russellville R.R. Co. | 1/75-1/80; added 7/81; eliminated 7/88; 1/94-7/2000 | | NRHS |
| 10 | DR | DARDANELLE & RUSSELLVILLE RAILROAD | | | PWRC |
| 11 | DR | Dardanelle and Russellville Railroad | | | RSRV |
| 12 | DR | DARDANELLE & RUSSELLVILLE RAILROAD | | | SCAC4 |
| 13 | DR | Deutsche Reichsbahn (DDR, 1945 - ) | | DDR | TRAFFIC |
| 14 | DR | Deutsche Regionalbahn | | DE | VKM |
| 15 | DR&U | Delaware River & Union R.R. | 4/1938 | | NAKINA |
| 16 | DR&U | Delaware River & Union R.R. Co. (Sun Oil Co.) | 7/1930 | | NAKINA |
| 17 | DR&U | Delaware River & Union R.R. Co. | 8/1920-7/1923 | | NAKINA |
| 18 | DR&U | Delaware River & Union R.R. Co. | 23-Jul | | NRHS |
| 19 | DR&U | Delaware River & Union R.R. | Apr-38 | | NRHS |
| 20 | DR&U | DELAWARE RIVER & UNION RAILROAD CO. (SUN OIL CO.) | | | PWRC |
| 21 | DRA | Dravidian Air Services Ltd. | Callsign: Firestone, | GB | AVCODES |
| 22 | DRA | Dravidian Air Services Ltd. | Callsign: Dravidian, | GB | AVCODES |
| 23 | DRA | Deer Air Co. Ltd. | | PRC | AVCODES |
| 24 | DRAA | DUDLEY, R A NURSERIES, INC | | | SCAC4 |
| 25 | DRAB | DURABOX PAPER INC | | | SCAC4 |
| 26 | DRABAS | Licencjonowane Przewozy Krajowe i Międzynarodowe Marcin Drabas | | PL | TRAFFIC |
| 27 | DRAC | DESERT RUNNER TRANSPORTATION INC. | | | SCAC4 |
| 28 | DRACH | Drachenfelsbahn Königswinter | | D | TRAFFIC |
| 29 | DRAD | D'EON, R A TRANSPORT LTD | | | SCAC4 |
| 30 | DRAGA | Drachen-Propan GmbH | | DE | VKM |
| 31 | DRAK | DRAKE PETROLEUM COMPANY INC | | | SCAC4 |
| 32 | DRAN | DURAN FREIGHT CORPORATION | | | SCAC4 |
| 33 | DRAO | DRAGON TRUCKING LTD | | | SCAC4 |
| 34 | DRAQ | D R A EXPRESS INC | | | SCAC4 |
| 35 | DRAR | DURAN ARVIZU, JOSE FRANCISCO | | | SCAC4 |
| 36 | DRAU | DRACONTAINERS CORP | | PA | BIC |
| 37 | DRAV | DALTON RIGGING & TRANSPORT INC | | | SCAC4 |
| 38 | DRAX | DRAYCUTT Corp. | added 7/1982; eliminated 1/1990 | | NAKINA |
| 39 | DRAX | Drake Tank Car Co. | added 1/1966; 10/1966-4/1970; eliminated 11/1973 | | NAKINA |
| 40 | DRAX | Drake Tank Car Co. | added 1/66; 10/66-4/70; eliminated 11/73 | | NRHS |
| 41 | DRAX | DRAYCUTT Corp. | added 7/82; eliminated 1/90 | | NRHS |
| 42 | DRAX | *DRAKE TANK CAR CO. | | | PWRC |
| 43 | DRAX | *DRAYCUTT CORP. | | | PWRC |
| 44 | DRAX | DRAYCUTT Corporation | | | RSRV |
| 45 | DRAY | DRAYCO LOGISTICS LLC | | | SCAC4 |
| 46 | DRB | Didier Rousset Buy | Callsign: Didier, | RCH | AVCODES |
| 47 | DRB | Didier Rousset Buy | | | ICAO1 |
| 48 | DRB | Deutsche Reichsbahn (1937-1945) | Real: DR | D | TRAFFIC |
| 49 | DRBA | DRIFT EXPLORATION DRILLING | | | SCAC4 |
| 50 | DRBB | DIAMOND RING SPECIALIZED LLC | | | SCAC4 |
| 51 | DRBC | D & R TRANSPORTATION | | | SCAC4 |
| 52 | DRBD | DREYER AND REINBOLD RACING | | | SCAC4 |
| 53 | DRBE | DART TRANSPORTATION | | | SCAC4 |
| 54 | DRBJ | DAVIS, RON TRUCKING | | | SCAC4 |
| 55 | DRBP | DRB TRANSPORT | | | SCAC4 |
| 56 | DRBR | DRB TRANSPORT INC | | | SCAC4 |
| 57 | DRC | Triton Airlines, Inc. | Callsign: Triton Air, | CDN | AVCODES |
| 58 | DRC | Triton Airlines | | | ICAO1 |
| 59 | DRC | DELAWARE RAILROAD CO. | | | PWRC |
| 60 | DRCA | DEOL ROAD CARRIER LTD | | | SCAC4 |
| 61 | DRCE | DIRECT EXPEDITERS INC | | | SCAC4 |
| 62 | DRCG | DIRECT TRUCKING INC | | | SCAC4 |
| 63 | DRCH | DREDGE, C. H.,&CO., INC. | | | SCAC1 |
| 64 | DRCK | DARR TRUCKING | | | SCAC4 |
| 65 | DRCL | Delaware River Coach Lines | an affiliate of Trans-Bridge Lines | US-NJ | TRAFFIC |
| 66 | DRCN | D R C ENTERPRISE INC | | | SCAC4 |
| 67 | DRCO | DIMARCO, P & CO INC | | | SCAC4 |
| 68 | DRCP | DOUBLE JR INC | | | SCAC4 |
| 69 | DRCT | DIRECT TRANSPORT INC | | | SCAC4 |
| 70 | DRCU | DELO LLC | | RUS | BIC |
| 71 | DRCW | DIRECT RIGHT CARTAGE 2001 INC | | | SCAC4 |
| 72 | DRCX | Martin Marietta Corp. | added 1/1979; 1/1980; eliminated 7/1986 | | NAKINA |
| 73 | DRCX | Martin-Marietta Cement, Division of Martin-Marietta Corp. | added 10/1972; 1/1975; eliminated 1/1979 | | NAKINA |
| 74 | DRCX | Dragon Cement Co., Division of Martin Marietta Corp. | added 7/1969; 4/1970; eliminated 10/1972 | | NAKINA |
| 75 | DRCX | Dragon Cement Co., Division of Martin Marietta Corp. | added 7/69; 4/70; eliminated 10/72 | | NRHS |
| 76 | DRCX | Martin-Marietta Cement, Division of Martin-Marietta Corp. | added 10/72; 1/75; eliminated 1/79 | | NRHS |
| 77 | DRCX | Martin Marietta Corp. | added 1/79; 1/80; eliminated 7/86 | | NRHS |
| 78 | DRCX | MARTIN MARIETTA CORP. [DENVER RAILWAY CAR COMPANY; DRAGON CEMENT CO.] | | | PWRC |
| 79 | DRCX | Denver Railway Car Company (Martin Marietta Corporation) | | | RSRV |
| 80 | DRCY | DAYTON RYDER CUP LLC | | | SCAC4 |
| 81 | DRCZ | DON RUSS COMPANY | | | PWRC |
| 82 | DRD | Dardanel Air Havacilik Ve Sanayi Ticaret A.S. | Callsign: Dardanel, | TR | AVCODES |
| 83 | DRD | Air Madrid Lineas Aereas, S.A. | IATA: NM, Callsign: Alada Air, IATA Prefix: 476, Ceased operations on 15 December 2006. ICAO designator changed from DRI | E | AVCODES |
| 84 | DRD | Air Madrid | IATA: NM | | ICAO1 |
| 85 | DRDA | DAFOE, D & R HOLDINGS LTD | | | SCAC4 |
| 86 | DRDH | DECKS RAILINGS & DESIGN | | | SCAC4 |
| 87 | DRDI | DRIVER DIRECT 1998 LIMITED | | | SCAC4 |
| 88 | DRDJ | DOLE ROAD CARRIERS | | | SCAC4 |
| 89 | DRDK | DESANTIS, D R TRUCKING | | | SCAC4 |
| 90 | DRDL | DIRECT DELIVERY AND DISTRIBUTION, INC | | | SCAC1 |
| 91 | DRDL | DIRECT DELIVERY AND DISTRIBUTION IN | | | SCAC4 |
| 92 | DRDN | DRD INTERNATIONAL INC | | | SCAC4 |
| 93 | DRDQ | DEFENCE RESEARCH & DEVELOPMENT (AWA | | | SCAC4 |
| 94 | DRDS | DEBRON DISTRIBUTION SERVICES INC | | | SCAC4 |
| 95 | DRDT | DESROCHE, D TRUCKING INC | | | SCAC4 |
| 96 | DRDV | DRW DE DEL RIO CD ACUNA SA DE CV | | | SCAC4 |
| 97 | DRDW | RAY, DON, DRIVE-A-WAY COMPANY OF CALIFORNIA, INC | | | SCAC3 |
| 98 | DRDX | The Duredo Co. | added 7/1979; 1/1980; eliminated 4/1986 | | NAKINA |
| 99 | DRDX | Duredo Co. (John H. Grace Co.) | 1/1950-1/1975; eliminated 7/1979 | | NAKINA |
| 100 | DRDX | Duredo Co., care of John H. Grace Co. | 4/1947 | | NAKINA |
