| 4101 | ENT | Dat Enterprise Limited | Callsign: Datent, | GB | AVCODES |
| 4102 | ENT | Air Hamilton | | NZ | AVCODES |
| 4103 | ENT | Enter Air Sp. z.o.o. | IATA: E4, Callsign: Enter, | PL | AVCODES |
| 4104 | ENT | Holmstorm Flyg AB | Callsign: Enterprise, | S | AVCODES |
| 4105 | ENT | DAT Enterprise Limited | | | ICAO1 |
| 4106 | ENT | Enter Air | | PL | TRAFFIC |
| 4107 | ENT | Banedanmark | | DK | VKM |
| 4108 | ENTA | ENTERPRISE TRANSPORTATION COMPANY | | | SCAC3 |
| 4109 | ENTA | ENTERPRISE TRANSPORTATION COMPANY | | | SCAC4 |
| 4110 | ENTB | E & N TRANSPORTATION | | | SCAC4 |
| 4111 | ENTC | ENERGY TRANSPORT COMPANY INC | | | SCAC3 |
| 4112 | ENTC | ESPINOZA TRUCKING | | | SCAC4 |
| 4113 | ENTE | ENTERPRISE TRANSPORT INC | | | SCAC4 |
| 4114 | ENTF | EAST END TRANSFER & STORAGE | | | SCAC3 |
| 4115 | ENTF | EAST END TRANSFER & STORAGE INC | | | SCAC4 |
| 4116 | ENTG | ENVIRONMENTAL TRANSPORT GROUP INC | | | SCAC3 |
| 4117 | ENTH | ENERGY TRUCKING INC | | | SCAC3 |
| 4118 | ENTK | ENTERPRISE TRUCKING SERVICE | | | SCAC3 |
| 4119 | ENTK | EDEN TRUCKING | | | SCAC4 |
| 4120 | ENTL | ENGELS TRUCK SERVICE | | | SCAC3 |
| 4121 | ENTN | ENVIRONMENTAL TRANSFER CORPORATION | | | SCAC3 |
| 4122 | ENTO | ENGINEERS TRANSPORT INC | | | SCAC3 |
| 4123 | ENTP | ENTERPRISE TRUCK LINE INC | | | SCAC3 |
| 4124 | ENTP | ENTERPRISE TRUCK LINE LLC | | | SCAC4 |
| 4125 | ENTQ | EIGHT NINE TWO ZERO SEVEN NINE (892 | | | SCAC3 |
| 4126 | ENTQ | ELLISON TRANSPORT INC | | | SCAC4 |
| 4127 | ENTR | ENTREPOT FRIGORIFIQUE INTERNATIONAL | | | SCAC4 |
| 4128 | ENTR | Euronaft Trzebinia Sp. Z o.o. | | PL | VKM |
| 4129 | ENTS | ENTSMINGER, JAMES F | | | SCAC3 |
| 4130 | ENTS | ETNA TRANSFER INC | | | SCAC4 |
| 4131 | ENTT | ENTERPRISE TRANSPORT INC | | | SCAC4 |
| 4132 | ENTU | ENTRANS AS | | N | BIC |
| 4133 | ENTU | ENTREPOSE S.A. | | | SCAC3 |
| 4134 | ENTW | EARNEST TRUCKING INC | | | SCAC3 |
| 4135 | ENTX | G.N.A., INC. T/A THE ENTERTRAINMENT LINE | | | PWRC |
| 4136 | ENUM | ENUMCLAW TRANSFER & STORAGE CO | | | SCAC3 |
| 4137 | ENV | Victoria Aviation | Callsign: Endeavour, | GB | AVCODES |
| 4138 | ENV | Victoria Aviation | | | ICAO1 |
| 4139 | ENVC | ENVIRONNEMENT E S A INC | | | SCAC4 |
| 4140 | ENVD | ENVENT ENGINEERING LTD | | | SCAC4 |
| 4141 | ENVG | ENVOY CARGA LOGISTICS | | | SCAC4 |
| 4142 | ENVI | ENVILOC GmbH | | DE | VKM |
| 4143 | ENVL | ENVIRONMENTAL LOGISTICS INC | | | SCAC4 |
| 4144 | ENVM | ENVIRONMENTAL TRUCKING COMPANY INC | | | SCAC3 |
| 4145 | ENVM | ENVIRONMENT CANADA | | | SCAC4 |
| 4146 | ENVO | ENVIRONMENTAL TECHNOLOGIES INTERNAT | | | SCAC3 |
| 4147 | ENVR | ENVIRONMENTAL INTERNATIONAL INC | | | SCAC3 |
| 4148 | ENVR | ENVIRO EXPRESS INC | | | SCAC4 |
| 4149 | ENVS | ENVISION TRANSPORT LTD | | | SCAC4 |
| 4150 | ENVT | ENVIRONMENTAL TRANSPORTATION SERVIC | | | SCAC3 |
| 4151 | ENVT | ENVIROTECH AG SYSTEMS LIMITED | | | SCAC4 |
| 4152 | ENVU | ENERGY SOLUTIONS LLC | | | SCAC4 |
| 4153 | ENVV | ENVIRONMENTAL INVESTIGATION AND ACT | | | SCAC3 |
| 4154 | ENVX | Energysolutions, LLC | added 7/2006 | | NAKINA |
| 4155 | ENVX | ENERGYSOLUTIONS, LLC | | | PWRC |
| 4156 | ENVX | ENERGYSOLUTIONS LLC | | | SCAC4 |
| 4157 | ENW | Aeronaves Del Noroeste | | | ICAO1 |
| 4158 | ENWA | ECOLIGHTS NW | | | SCAC4 |
| 4159 | ENWT | ENVIRONMENTAL WASTE TECHNOLOGY | | | SCAC3 |
| 4160 | ENWT | EAST & WEST TRANSPORTATION | | | SCAC4 |
| 4161 | ENX | Enex Aviation Ltd | Callsign: Genesis, | GB | AVCODES |
| 4162 | ENXC | EAGLESON TRANSPORT LLC | | | SCAC4 |
| 4163 | ENXK | E N E KASSOS LTD | | | SCAC3 |
| 4164 | ENXL | ENERGEX AMERICAN INC | | | SCAC4 |
| 4165 | ENXX | ENX Inc. | added 4/2006; eliminated 10/2006 | | NAKINA |
| 4166 | ENXX | ENX, INC. | | | PWRC |
| 4167 | ENXX | ENX INC | | | SCAC4 |
| 4168 | ENY | Envoy Air, Inc. | IATA: MQ, Callsign: Envoy, IATA Prefix: 093, Name changed from American Eagle Airlines, Inc. d/b/a American Eagle, Inc. ICAO designator changed from EGF. ICAO Callsign changed from Eagle Flight. Designator MQ reinstated by IATA | USA | AVCODES |
| 4169 | ENYD | ENERGY DISPATCH LLC | | | SCAC4 |
| 4170 | ENYL | ENERGY LABS INC | | | SCAC4 |
| 4171 | ENYU | EAST NEW YORK UTILITIES-ALBANY SOUTHERN | | | PWRC |
| 4172 | ENZ | Jota Aviation Ltd | Callsign: Enzo, | GB | AVCODES |
| 4173 | ENZK | E N E KERKYRA | | | SCAC3 |
| 4174 | ENZL | ENTZEL, GERALD TRUCKING | | | SCAC4 |
| 4175 | ENZN | ENZIAN SHIP MANAGEMENT AG | | | SCAC4 |
| 4176 | ENZR | ENZOR TRAVEL SERVICE | | | SCAC3 |
| 4177 | ENZR | ESPINOZA ZAVALA, ROGELIO MANUEL | | | SCAC4 |
| 4178 | EO | Congo Airlines | ICAO: ALX, Callsign: All Congo, Name changed to Hewa Bora Airways. Designator EO* reinstated by IATA | ZRE | AVCODES |
| 4179 | EO | Express One International, Inc. | ICAO: LHN, Callsign: Longhorn, Found in 1983. Ceased operations. | USA | AVCODES |
| 4180 | EO | Alliance Airlines Sprl | ICAO: ALX, Callsign: All Congo, Name changed to Congo Airlines | ZRE | AVCODES |
| 4181 | EO | Euroflite | Formed by Cabair and Executive Express for schedules services. | GB | AVCODES |
| 4182 | EO | Hewa Bora Airways | ICAO: ALX, Callsign: All Congo, IATA Prefix: 663, Founded in 1994. Ceased operations in 2011. Name changed from Congo Airlines. Designator EO* reinstated by IATA | ZRE | AVCODES |
| 4183 | EO | flyCongo | ICAO: ALX, Callsign: Allcongo, IATA Prefix: 663, Founded in 2012. Commenced operations on 24 March 2012. Ceased operations in October 2012 when merged into Compagnie Africaine d'Aviation (CAA). Formerly Hewa Bora Airways | ZRE | AVCODES |
| 4184 | EO | Air Go Egypt | ICAO: AGY, Callsign: Egyptian Bird, Designator EO recalled by IATA | ET | AVCODES |
| 4185 | EO | Ikar, LLC t/a Pegas Fly | ICAO: KAR, Callsign: Krasjet, IATA Prefix: 770, Founded on 15 June 1993. IATA designator changed from IK*. Name changed from Ikar, LLC. | RUS | AVCODES |
| 4186 | EOA | Elilombarda S.R.L. | Callsign: Lombarda, | I | AVCODES |
| 4187 | EOA | Elilombarda | | | ICAO1 |
| 4188 | EOAN | ESQUIVEL OCHOA, ADRIAN | | | SCAC4 |
| 4189 | EOCA | ENSCO OFFSHORE COMPANY | | | SCAC4 |
| 4190 | EOCL | EDWARDS OIL COMPANY OF | | | SCAC4 |
| 4191 | EOCN | ECHOLS OIL CO INC | | | SCAC4 |
| 4192 | EOCO | EDDYVILLE OIL COMPANY | | | SCAC3 |
| 4193 | EOCO | ENVIRONMENT CANADA EMISSIONS RESEAR | | | SCAC4 |
| 4194 | EOCT | EOC TRANSPORT | | | SCAC4 |
| 4195 | EOCW | EASTPORT OCEAN TRADING CORP | | | SCAC4 |
| 4196 | EOCX | Ensign Oil Co., Inc. | 8/1920 | | NAKINA |
| 4197 | EOCX | ENSIGN OIL CO., INC. | | | PWRC |
| 4198 | EOCY | EDISON OIL COMPANY | | | SCAC4 |
| 4199 | EODI | EXPAND-O DISTRIBUTION WAREHOUSING S | | | SCAC3 |
| 4200 | EODN | EOD LOGISTICS INC | | | SCAC4 |
