| 4401 | EPL | Aero Transportes Empresariales | Callsign: Empresariales, | MEX | AVCODES |
| 4402 | EPL | Aero Transportes Empresariales | | | ICAO1 |
| 4403 | EPLA | EL PASO-LOS ANGELES LIMOUSINE EXPRE | | | SCAC3 |
| 4404 | EPLD | EPLAND TRUCKING INC | | | SCAC3 |
| 4405 | EPLD | ENGINEERED PLASTIC DESIGNS INC | | | SCAC4 |
| 4406 | EPLE | EXPRESSLAND SERVICES LLC | | | SCAC4 |
| 4407 | EPLG | EPIC LOGISTICS INC | | | SCAC4 |
| 4408 | EPLM | E P L EXPRESS | | | SCAC4 |
| 4409 | EPLN | EXPRESS LINES LTD | | | SCAC4 |
| 4410 | EPLO | EP LOGISTICS INC | | | SCAC4 |
| 4411 | EPLS | ESPOSITOS LIMOUSINE SERVICE INC | | | SCAC3 |
| 4412 | EPLT | EP LOGISTICS | | | SCAC4 |
| 4413 | EPLU | EPL INTERNATIONAL PTY LTD | | AUS | BIC |
| 4414 | EPLX | The Eagle-Picher Co. | 1/1946-4/1947 | | NAKINA |
| 4415 | EPLX | The Eagle-Picher Lead Co. | 7/1935-1/1945 | | NAKINA |
| 4416 | EPLX | The Eagle-Picher Lead Co. | Apr-38 | | NRHS |
| 4417 | EPLX | EAGLE-PITCHER CO. [EAGLE-PITCHER LEAD CO.] | | | PWRC |
| 4418 | EPMA | EPM ASPHALTEC INC | | | SCAC4 |
| 4419 | EPMC | EXPRESS MOTOR CARRIERS INC | | | SCAC3 |
| 4420 | EPMC | ELAINE PETROLEUM DIST INC | | | SCAC4 |
| 4421 | EPML | EXPRESSWAY MINICOACH LTD | | | SCAC3 |
| 4422 | EPML | EPES TRANSPORT SYSTEM INCORPORATED | | | SCAC4 |
| 4423 | EPMN | EAST PENN MANUFACTURING CO INC | | | SCAC4 |
| 4424 | EPMS | EXPERT MESSENGER SERVICE INC | | | SCAC3 |
| 4425 | EPMX | The Eagle-Picher Co. | 1/1946-4/1947 | | NAKINA |
| 4426 | EPMX | The Eagle-Picher Mining & Smelting Co. | 7/1937-1/1945 | | NAKINA |
| 4427 | EPMX | The Eagle-Picher Mining & Smelting Co. | Apr-38 | | NRHS |
| 4428 | EPMX | EAGLE-PITCHER CO. [EAGLE-PITCHER MINING & SMELTING CO.] | | | PWRC |
| 4429 | EPN | Europlane, S.L. | Callsign: Europlane, | E | AVCODES |
| 4430 | EPNC | EPIC TRANS LLC | | | SCAC4 |
| 4431 | EPNL | ECONOMY PROPANE LLC | | | SCAC4 |
| 4432 | EPNP | ENAMEL PRODUCTS & PLATING COMPANY | | | SCAC3 |
| 4433 | EPNS | ESPOSITO AND SONS FREIGHT LINES, INC | | | SCAC3 |
| 4434 | EPNS | ESPOSITO AND SONS FREIGHT LINES INC | | | SCAC4 |
| 4435 | EPNX | El Paso Natural Gas Co. | 1/1952-10/1957; eliminated 7/1959 | | NAKINA |
| 4436 | EPNX | El Paso Natural Gas Co. | 1/52-10/57; eliminated 7/59 | | NRHS |
| 4437 | EPNX | EL PASO NATURAL GAS CO. | | | PWRC |
| 4438 | EPO | EPORE Sp. z o.o. | | PL | VKM |
| 4439 | EPOI | EXPRESS ONE (1) INC | | | SCAC3 |
| 4440 | EPOOL | EUROPOOL GmbH | | DE | VKM |
| 4441 | EPP | ELIXIR PRAHOVO DOO PRAHOVO | | RS | VKM |
| 4442 | EPPQ | EPPER TRUCKING CO | | | SCAC3 |
| 4443 | EPPQ | EXPRO TRANSIT LOGISTIC INC | | | SCAC4 |
| 4444 | EPPR | EPPS SHIPPING | | | SCAC4 |
| 4445 | EPPS | EPPS TRUCKING INC | | | SCAC4 |
| 4446 | EPPT | EPPINGER TRANSPORTATION | | | SCAC3 |
| 4447 | EPPT | EPP TRUCKING INC | | | SCAC4 |
| 4448 | EPPU | SCANDIC CONTAINER OY | | FIN | BIC |
| 4449 | EPPU | SCANDIC CONTAINER OY | | | SCAC4 |
| 4450 | EPPV | EPPS SERVICE INC | | | SCAC4 |
| 4451 | EPPX | A.R. Eppenauer | 1/1950-1/1952; eliminated 7/1953 | | NAKINA |
| 4452 | EPPX | A.R. Eppenauer | Jan-52 | | NRHS |
| 4453 | EPPX | A. R. EPPENAUER | | | PWRC |
| 4454 | EPR | Expreso Aereo | Callsign: Expreso Aereo, | PE | AVCODES |
| 4455 | EPR | Express Airways, D.o.o. | Callsign: Emperor, | SLO | AVCODES |
| 4456 | EPR | E-P Rail Romani | | RO | TRAFFIC |
| 4457 | EPRA | EPICENTER AQUACULTURE INC | | | SCAC4 |
| 4458 | EPRC | EXPRESS PRODUCE CO INC | | | SCAC3 |
| 4459 | EPRC | ENTREPRISES FORESTIERES RE-AN INC | | | SCAC4 |
| 4460 | EPRE | EMPIRE WAREHOUSE INC | | | SCAC3 |
| 4461 | EPRE | EMPIRE WAREHOUSE INC | | | SCAC4 |
| 4462 | EPRK | EPARKA SHIPPING INC. | | | SCAC3 |
| 4463 | EPRL | EXPO PROS LTD | | | SCAC3 |
| 4464 | EPRN | EMPRESA | | | SCAC4 |
| 4465 | EPRO | EDWARDS PRO-TECH LTD | | | SCAC4 |
| 4466 | EPRP | EXPRESS PLUS | | | SCAC4 |
| 4467 | EPRR | EXPLORERS TRANSPORT INC | | | SCAC4 |
| 4468 | EPRS | EMPIRE STATE MARINE CO INC | | | SCAC3 |
| 4469 | EPRS | EXPRESS RALEIGH SA DE CV | | | SCAC4 |
| 4470 | EPRT | EPLEY, RALPH L TRUCKING | | | SCAC3 |
| 4471 | EPRU | ENICHEM POLIMERI | | | SCAC3 |
| 4472 | EPRY | East Penn Railroad LLC | added 10/2007 | | NAKINA |
| 4473 | EPRY | East Penn Ry., Inc. | added 1/1996; 7/2000-7/2005; eliminated 7/2005 | | NAKINA |
| 4474 | EPRY | East Penn Ry., Inc. | added 1/96; 7/2000 | | NRHS |
| 4475 | EPRY | EAST PENN RAILWAY | | | PWRC |
| 4476 | EPRY | East Penn Railway | | | RSRV |
| 4477 | EPRY | EAST PENN RAILWAYS INC | | | SCAC4 |
| 4478 | EPS | Epps Air Service, Inc. | Callsign: Epps Air, | USA | AVCODES |
| 4479 | EPS | Epps Air Service | | | ICAO1 |
| 4480 | EPSC | EXPRESS SERVICES CO | | | SCAC3 |
| 4481 | EPSC | Epsom Coaches | | GB | TRAFFIC |
| 4482 | EPSE | EMPIRE STEEL | | | SCAC4 |
| 4483 | EPSG | EPES LOGISTICS SERVICES INC | | | SCAC4 |
| 4484 | EPSI | EDGEWATER TRANSPORT SYSTEM INC | | | SCAC3 |
| 4485 | EPSK | EPS RB KOLUBARA d.o.o LAZAREVAC | | RS | VKM |
| 4486 | EPSL | EPAULET SHIPPING COMPANY LIMITED | | | SCAC3 |
| 4487 | EPSM | EMPRESA | | | SCAC4 |
| 4488 | EPSP | EL PASO TRANSPORTATION SERVICES | | | SCAC4 |
| 4489 | EPSR | ENTREPRISE SANRIC INC | | | SCAC4 |
| 4490 | EPSS | EQUIPMENT STORAGE & SERVICE INC | | | SCAC3 |
| 4491 | EPSS | EQUIPMENT STORAGE & SERVICE INC | | | SCAC4 |
| 4492 | EPSU | GAZSERVIS LTD | | | SCAC4 |
| 4493 | EPSY | EXPRESS PACKAGE SYSTEMS | | | SCAC3 |
| 4494 | EPTA | E P TRANSPORTATION INC | | | SCAC3 |
| 4495 | EPTB | EXPRESS TRANSFERS | | | SCAC4 |
| 4496 | EPTC | Oregon Pacific R.R. Co. | 7/2005 | | NAKINA |
| 4497 | EPTC | East Portland Traction Co. | 1/1994-7/2000 | | NAKINA |
| 4498 | EPTC | East Portland Traction Co. | 1/94-7/2000 | | NRHS |
| 4499 | EPTC | *EAST PORTLAND TRACTION COMPANY | | | PWRC |
| 4500 | EPTC | +OREGON PACIFIC RAILROAD CO. | | | PWRC |
