| 5301 | ESLC | EASY LINE COSMETICS | | | SCAC4 |
| 5302 | ESLD | ESSLING, DON | | | SCAC3 |
| 5303 | ESLE | E S L ENTERPRISES | | | SCAC3 |
| 5304 | ESLE | ESL EXPRESS INC | | | SCAC4 |
| 5305 | ESLF | ETELA-SUOMEN LAIVA OY | | | SCAC3 |
| 5306 | ESLG | E & S LEASING | | | SCAC4 |
| 5307 | ESLI | ESTATE LINES INC | | | SCAC3 |
| 5308 | ESLJ | (The) East St. Louis Junction R.R. | 7/1935-10/1966; eliminated 10/1974; 1/1975; added 7/1979; 1/1980; eliminated 10/1992; 1/1994-7/2005 | | NAKINA |
| 5309 | ESLJ | East St. Louis Junction R.R. (Terminal R.R. Association of St. Louis) | 7/1932 | | NAKINA |
| 5310 | ESLJ | East St. Louis Junction R.R. | 7/1930 | | NAKINA |
| 5311 | ESLJ | East St. Louis Junction R.R. | 4/38-10/66; eliminated 10/74; 1/75; added 7/79; 1/80; eliminated 10/92; 1/94-7/2000 | | NRHS |
| 5312 | ESLJ | TERMINAL RAILROAD ASSOCIATION OF ST. LOUIS [EAST ST. LOUIS JUNCTION RR] | | | PWRC |
| 5313 | ESLJ | East St. Louis Junction Railroad | | | RSRV |
| 5314 | ESLJ | EAST ST. LOUIS JUNCTION RAILROAD CO | | | SCAC3 |
| 5315 | ESLJ | EAST ST LOUIS JUNCTION RR | | | SCAC4 |
| 5316 | ESLK | ECOMAX SERVICES LLC | | | SCAC4 |
| 5317 | ESLL | EXCLUSIVE LIMOUSINE SERVICE OF LIVI | | | SCAC3 |
| 5318 | ESLM | ENERGY SUPPLY LLC | | | SCAC4 |
| 5319 | ESLN | EASTSHORE LINES | | | SCAC3 |
| 5320 | ESLO | ESCORT LIMOUSINE SERVICE | | | SCAC3 |
| 5321 | ESLQ | EXPEDITED SPECIALIZED LOGISTICS LLC | | | SCAC4 |
| 5322 | ESLR | EMGITI SHIPPING LTD | | | SCAC4 |
| 5323 | ESLS | EAST LIBERTY SERVICES INC | | | SCAC3 |
| 5324 | ESLS | ESA, LOUIS TRUCKING | | | SCAC4 |
| 5325 | ESLU | ETHIOPIAN SHIPPING & LOGISTICS SERVICES ENTERPRISE | | ETH | BIC |
| 5326 | ESLU | ECUADORIAN STATE LINE | | | SCAC3 |
| 5327 | ESLU | ETHIOPIAN SHIPPING LINES | | | SCAC4 |
| 5328 | ESLV | ESL EXPRESS INC | | | SCAC4 |
| 5329 | ESLW | EAGLE SHIPPING LTD | | | SCAC4 |
| 5330 | ESLX | ESSROC LOGANSPORT | | | PWRC |
| 5331 | ESLZ | EAST ST. LOUIS JUNCTION RR | | | PWRC |
| 5332 | ESLZ | East St. Louis Junction Railroad | | | RSRV |
| 5333 | ESLZ | EAST ST LOUIS JUNCTION RR | | | SCAC4 |
| 5334 | ESM | Executive Aircraft Services S.A.L. | Callsign: Exec Aircraft, | RL | AVCODES |
| 5335 | ESMC | EASTMAN COACH LINES INC | | | SCAC3 |
| 5336 | ESMC | EXPLORER SPECIAL MARITIME ENTERPRIS | | | SCAC4 |
| 5337 | ESMD | EXPRESS SIXTY-MINUTES DELIVERY SERV | | | SCAC3 |
| 5338 | ESME | EMPIRE STATE MOTOR EXPRESS, INC | | | SCAC3 |
| 5339 | ESMG | EMPIRE STATE MESSENGER SERVICE INC | | | SCAC3 |
| 5340 | ESMH | E S MOBILE HOME MOVING | | | SCAC3 |
| 5341 | ESML | ERICKSON MFG LTD | | | SCAC4 |
| 5342 | ESMM | ESTEEM MARITIME PTE LTD | | | SCAC4 |
| 5343 | ESMN | ENGAS SHIP MANAGEMENT A/S | | | SCAC3 |
| 5344 | ESMQ | EPTALOFOS SPECIAL MARITIME ENTERPRI | | | SCAC4 |
| 5345 | ESMS | EUROSTAR MARITIME S A | | | SCAC4 |
| 5346 | ESMT | EASTMAN TRANSPORT, INC | | | SCAC3 |
| 5347 | ESMT | EASTMAN TRANSPORT INC | | | SCAC4 |
| 5348 | ESMV | EASTERN MOVING & STORAGE INC | | | SCAC3 |
| 5349 | ESMW | ENZIAN SHIP MANAGEMENT (DEUTSCHLAND | | | SCAC4 |
| 5350 | ESMX | Essem Corp. | added 4/1969; 4/1970-1/1980; eliminated 7/1985 | | NAKINA |
| 5351 | ESMX | Essem Corp. | added 4/69; 4/70-1/80 | | NRHS |
| 5352 | ESMX | ESSEM CORP. | | | PWRC |
| 5353 | ESMX | Essem Corporation | | | RSRV |
| 5354 | ESMY | E & S MOTOR FREIGHT | | | SCAC4 |
| 5355 | ESN | Euro Sun | | | ICAO1 |
| 5356 | ESNA | ESCONDIDO AVOCADO TRANSPORT | | | SCAC3 |
| 5357 | ESNC | EAST INC, TAMPA FL | | | SCAC3 |
| 5358 | ESNF | ESTENSON LOGISTICS LLC (FLATBED DIV | | | SCAC4 |
| 5359 | ESNH | EASTERN HAULERS INC | | | SCAC3 |
| 5360 | ESNK | EASTON TRUCKING INC | | | SCAC4 |
| 5361 | ESNL | ESTENSON LOGISTICS LLC | | | SCAC4 |
| 5362 | ESNN | ESPINOSA TRANSFER | | | SCAC4 |
| 5363 | ESNR | ESSEN TRANSPORT LTD | | | SCAC4 |
| 5364 | ESNS | ESTES & SONS TRUCKING | | | SCAC3 |
| 5365 | ESNV | ESTORIL NAVIGATION LTD | | | SCAC4 |
| 5366 | ESNW | ELITE SPAS NORTHWEST | | | SCAC4 |
| 5367 | ESO | Avitat | | GB | AVCODES |
| 5368 | ESO | Avitat | | | ICAO1 |
| 5369 | ESOD | EXPRESS-1 DEDICATED | | | SCAC4 |
| 5370 | ESOI | ESTES OIL | | | SCAC4 |
| 5371 | ESOL | EASTERN OIL COMPANY | | | SCAC4 |
| 5372 | ESOM | ELSOME | | | SCAC4 |
| 5373 | ESON | EASON PETROLEUM INC | | | SCAC4 |
| 5374 | ESOS | ESPOSITO & SON TOURS INC | | | SCAC3 |
| 5375 | ESOT | EASSONS TRANSPORT LTD | | | SCAC3 |
| 5376 | ESOT | EASSONS TRANSPORT LTD | | | SCAC4 |
| 5377 | ESOV | EXPERT SERVICES OF VIRGINIA INC | | | SCAC4 |
| 5378 | ESOX | Empire State Refining Co. | 1/1943 | | NAKINA |
| 5379 | ESOX | EMPIRE STATE REFINING CO. | | | PWRC |
| 5380 | ESP | Espeair | Callsign: Espeair, Ceased operations | CZ | AVCODES |
| 5381 | ESP | Esperia Aviation Services S.p.A. | | I | AVCODES |
| 5382 | ESPA | ESPARZA, LEO TRUCKING | | | SCAC3 |
| 5383 | ESPC | ESPINOSA CARTAGE COMPANY | | | SCAC3 |
| 5384 | ESPC | ESP TRANSPORTATION INC | | | SCAC4 |
| 5385 | ESPD | ESTATE PRODUCTS INC | | | SCAC4 |
| 5386 | ESPE | ESPENSHIP MOVING AND STORAGE INC | | | SCAC3 |
| 5387 | ESPG | ESPINOZA GUAJARDO, JOSE EDUARDO | | | SCAC4 |
| 5388 | ESPI | EASTPORT INTERMODAL CORP | | | SCAC3 |
| 5389 | ESPK | ESP TRANSPORTATION LLC | | | SCAC4 |
| 5390 | ESPL | ESTEP LOGISTICS INC | | | SCAC4 |
| 5391 | ESPM | ESCARPMENT TRANSPORTATION SYSTEMS I | | | SCAC3 |
| 5392 | ESPN | East Penn Railroad LLC | added 10/2007 | | NAKINA |
| 5393 | ESPN | EAST PENN RAILROAD LLC | | | PWRC |
| 5394 | ESPN | EAST PENN RAILROAD LLC | | | SCAC4 |
| 5395 | ESPN | East Penn Railroad LLC | | USA | TRAFFIC |
| 5396 | ESPO | ESPOSITO TRUCKING INC | | | SCAC3 |
| 5397 | ESPO | EXPRESS STEPHANE PELLETIER INC | | | SCAC4 |
| 5398 | ESPQ | EAGLE STEEL PRODUCTS INC | | | SCAC4 |
| 5399 | ESPR | ESPARZA EXPRESS | | | SCAC4 |
| 5400 | ESPT | ESPINOSA TRUCKING COMPANY | | | SCAC4 |
