| 601 | EBTG | E & B TRUCKING INC | | | SCAC3 |
| 602 | EBTG | EL BACH TRUCKING INC | | | SCAC4 |
| 603 | EBTH | EAST BAY TRANSPORT INC | | | SCAC4 |
| 604 | EBTI | EIGHT BALL TRUCKING | | | SCAC3 |
| 605 | EBTJ | EC BROS TRANSPORT | | | SCAC4 |
| 606 | EBTN | EASTERN BULK TRANSPORT INC | | | SCAC4 |
| 607 | EBTN | East Broad Top Railroad | Real: EBT | USA | TRAFFIC |
| 608 | EBTO | ELLIOTT BAY SERVICE TRANSFER | | | SCAC3 |
| 609 | EBTO | ELLIOTT BAY SERVICE TRANSFER | | | SCAC4 |
| 610 | EBTQ | EBORN TRUCK SERVICE | | | SCAC3 |
| 611 | EBTQ | E & B TRANSPORT INC | | | SCAC4 |
| 612 | EBTR | E B TRANS CO, INC | | | SCAC3 |
| 613 | EBTX | English Boiler & Tube Inc. | added 10/2003; 7/2005; eliminated 1/2007 | | NAKINA |
| 614 | EBTX | ENGLISH BOILER & TUBE INC. | | | PWRC |
| 615 | EBTX | ENGLISH BOILER & TUBE INC | | | SCAC4 |
| 616 | EBU | Delta AirElite Business Jets | Callsign: Elite Blue, ICAO designator changed to ELJ. ICAO callsgin changed to Elite Jet. Delta's Business Jets | USA | AVCODES |
| 617 | EBUC | EASTERN BULK CARRIERS AS | | | SCAC4 |
| 618 | EBUL | EUROBULK LTD | | | SCAC4 |
| 619 | EBUL | European Bulls | | EU | TRAFFIC |
| 620 | EBUS | EATMAN BUS CHARTER SERVICE | | | SCAC3 |
| 621 | EBUS | Eurobus | renamed from SAD KDS (Kosice) in 2007 | SK | TRAFFIC |
| 622 | EBV | Aerbrava S.C.P. | | E | AVCODES |
| 623 | EBVN | EBERT VANS INC | | | SCAC3 |
| 624 | EBVS | EDWARDS BROS VAN & STORAGE CO | | | SCAC3 |
| 625 | EBVS | EVASHENK | | | SCAC4 |
| 626 | EBW | Eisenbahn-Bewachungs GmbH | Dachau | D | privat-bahn.de |
| 627 | EBW | Eisenbahn-Bewachungs GmbH, NL Cargo | | D | TRAFFIC |
| 628 | EBW | Eisenbahnbewachungs-GmbH | | DE | VKM |
| 629 | EBXQ | EARLYBIRD EXPRESS | | | SCAC3 |
| 630 | EBYB | EBY BROTHERS INC | | | SCAC3 |
| 631 | EBYB | EBY BROTHERS INC | | | SCAC4 |
| 632 | EBYR | EBY TRANSPORT INC | | | SCAC4 |
| 633 | EBYS | EBY SAWMILL | | | SCAC4 |
| 634 | EBZX | Ebenezer Railcar Services, Inc. | added 10/2008 | | NAKINA |
| 635 | EBZX | EBENEZER RAILCAR SERVICES, INC. | | | PWRC |
| 636 | EBZX | EBENEZER RAILCAR SERVICES INC | | | SCAC4 |
| 637 | EC | Avialeasing Aviation Company | ICAO: TWN, Callsign: Twinarrow, Designator EC recalled by IATA. IATA designator changed from AD* | UZ | AVCODES |
| 638 | EC | Heli Inter Riviera | ICAO: HIN, Callsign: Heli Inter, Designator EC* recalled by IATA. Name changed from Heli-Inter SA. | F | AVCODES |
| 639 | EC | Heli-Inter SA | ICAO: HIN, Callsign: Heli Inter, Name changed to Heli Inter Riviera | F | AVCODES |
| 640 | EC | Anglo Airlines Ltd. d/b/a Anglo Cargo Ltd. | ICAO: ANC, Callsign: Anglo, Ceased operations | GB | AVCODES |
| 641 | EC | East African Airways Corporation | Callsign: Eastaf, | EAK | AVCODES |
| 642 | EC | Air Ecosse | | GB | AVCODES |
| 643 | EC | BA European Limited t/a Openskies | ICAO: BOS, IATA Prefix: 284, | GB | AVCODES |
| 644 | EC | Elysair S.A.S. d/b/a L'Avion | ICAO: AVI, IATA Prefix: 284, Merged into Openskies. IATA designator changed from A0. | F | AVCODES |
| 645 | EC | OpenSkies | ICAO: AVI, IATA Prefix: 284, Name changed from Elysair S.A.S. d/b/a L'Avion. Merged into Openskies. IATA designator changed from A0 | F | AVCODES |
| 646 | EC | Openskies | ICAO: BOS, Callsign: Mistral, IATA Prefix: 284, IATA code changed to LV | F | AVCODES |
| 647 | EC | easyJet Europe Airline GmbH | ICAO: EJU, Callsign: Alpine, | A | AVCODES |
| 648 | EC | East African Airways | | EAK | TRAFFIC |
| 649 | ECA | Eurocypria Airlines Ltd. | IATA: UI, Callsign: Eurocypria, IATA Prefix: 475, Liquidated on 29 November 2010 after EU failed to approve merger with Cyprus Airways | CY | AVCODES |
| 650 | ECA | Eagle Commuter Airlines | Callsign: Eagleair, | USA | AVCODES |
| 651 | ECA | OHL Air Charterflug GmbH & Co. KG | Callsign: Dark Knight, Name changed to Excellent Air GmbH. | D | AVCODES |
| 652 | ECA | Excellent Air GmbH | Callsign: Dark Knight, Name changed from OHL Air Charterflug GmbH & Co. KG. | D | AVCODES |
| 653 | ECA | Eurocypria Airlines | IATA: UI | | ICAO1 |
| 654 | ECA | Eisenbahnclub Aschersleben e.V. | Aschersleben | D | privat-bahn.de |
| 655 | ECAA | EXPRESS FUELS INC | | | SCAC4 |
| 656 | ECAD | ENTERPRISE CRUDE OIL LLC | | | SCAC4 |
| 657 | ECAE | EYE CARE ALLIANCE LLC | | | SCAC4 |
| 658 | ECAG | EAST COAST AUTO LOGISTICS LLC | | | SCAC4 |
| 659 | ECAI | EMERALD COAST AIR FREIGHT | | | SCAC3 |
| 660 | ECAJ | ECOTURISTICA | | | SCAC4 |
| 661 | ECAM | ECAM CONTAINER AGENCIES INC | | | SCAC3 |
| 662 | ECAO | ELM CITY AUTO REPAIR LLC | | | SCAC4 |
| 663 | ECAR | ECONOMY CARRIERS LIMITED | | | SCAC3 |
| 664 | ECAR | ECL TRANSPORTATION LTD | | | SCAC4 |
| 665 | ECAU | ENERCON GMBH | | D | BIC |
| 666 | ECAU | ENERCON GMBH | | | SCAC4 |
| 667 | ECAU | ELETRIC Schaltanlagenfertigung GmbH | | DE | VKM |
| 668 | ECB | European Coastal Airlines Ltd. | IATA: H5, Callsign: Coastal Clipper, IATA designator changed to WL | HR | AVCODES |
| 669 | ECB | European Coastal Airlines Ltd. | IATA: WL, Callsign: Coastal Clipper, Ceased operations October 2016. IATA designator changed from H5 | HR | AVCODES |
| 670 | ECB | European Coastal Airlines | | | ICAO1 |
| 671 | ECB | ELECTROCARBON SLATINA SA | | RO | VKM |
| 672 | ECBK | EMERY CUSTOMS BROKERS | | | SCAC3 |
| 673 | ECBK | EMERY CUSTOMS BROKERS | | | SCAC4 |
| 674 | ECBL | EXPRESS CASA BLANCA | | | SCAC4 |
| 675 | ECBN | EXCAVATION CLAUDE BRETON | | | SCAC4 |
| 676 | ECBR | East Cooper and Berkeley R.R. Co. | added 7/1978; 1/1980-7/2000; eliminated 10/2003; 7/2005 | | NAKINA |
| 677 | ECBR | East Cooper and Berkeley R.R. Co. | added 7/78; 1/80-7/2000 | | NRHS |
| 678 | ECBR | EAST COOPER & BERKELEY RAILROAD COMPANY | | | PWRC |
| 679 | ECBR | East Cooper and Berkeley Railroad | | | RSRV |
| 680 | ECBR | EAST COOPER AND BERKELEY RAILROAD C | | | SCAC3 |
| 681 | ECBS | EASTERN CARIBBEAN STEEL IMPORTERS | | | SCAC3 |
| 682 | ECBT | ECONOCARIBE TRUCKING | | | SCAC3 |
| 683 | ECBU | EUROPEAN CONTAINERS NV | | B | BIC |
| 684 | ECBU | EUROPEAN CONTAINERS NV | | | SCAC4 |
| 685 | ECBY | EAST COAST BOAT & YACHT HAULING LLC | | | SCAC4 |
| 686 | ECC | ECA (Europe Continental Airways) d/b/a/ Crossair Europe | IATA: QE, Callsign: Cigigne, Name changed from Europe Continental Airways (ECA) | CH | AVCODES |
| 687 | ECC | Europe Continental Airways (ECA) | IATA: QE, Callsign: Cigigne, Name changed to ECA (Europe Continental Airways) d/b/a/ Crossair Europe. Name changed from European Continental Airways (ECA) | CH | AVCODES |
| 688 | ECC | European Continental Airways (ECA) | IATA: QE, Callsign: Cigigne, Name changed to Europe Continental Airways (ECA) | CH | AVCODES |
| 689 | ECC | Éclair Aviation | Callsign: �clair, | CZ | AVCODES |
| 690 | ECC | Crossair Europe | IATA: QE | | ICAO1 |
| 691 | ECC | EMPIRE COKE COMPANY | | | PWRC |
| 692 | ECC | EAST COAST CARRIERS CONFERENCE | | | SCAC4 |
| 693 | ECCA | ECCA FREIGHT SYSTEMS NEW YORK | | | SCAC3 |
| 694 | ECCA | EXPRESS LOGISTICS INC | | | SCAC4 |
| 695 | ECCD | ENGLISH CONSTRUCTION CO INC | | | SCAC4 |
| 696 | ECCE | EXPRESS CONNECTION CARRIERS INC | | | SCAC4 |
| 697 | ECCG | EXCEL CARTAGE INC | | | SCAC3 |
| 698 | ECCG | ELMAN TRUCKING INC | | | SCAC4 |
| 699 | ECCH | EFFICIENCY COMPANIES INC | | | SCAC4 |
| 700 | ECCI | EXHIBITION CONTRACTORS CO INC | | | SCAC3 |
