| 401 | ZMCHK | Zakłady Metalowo-Chemiczne METCHEM Andrzej Świerczek | | PL | VKM |
| 402 | ZMCI | ZUMMO MEAT COMPANY INC | | | SCAC4 |
| 403 | ZMCO | ZAMCO TRANSPORT SPECIALIST INC | | | SCAC4 |
| 404 | ZMDC | ZMD EXPRESS | | | SCAC4 |
| 405 | ZMEI | Z MOLD & ENGINEERING INC | | | SCAC4 |
| 406 | ZMFC | XTRA INTERMODAL | | | PWRC |
| 407 | ZMFC | XTRA Intermodal | | | RSRV |
| 408 | ZMFC | ZIEMAN MANUFACTURING CO | | | SCAC4 |
| 409 | ZMIE | ZIP MAIL ISLAND EXPRESS | | | SCAC4 |
| 410 | ZMKSST | Zakład Miejski Komunikacji Samochodowej Stalowa Wola | City: Stalowa Wola | PL | TRAFFIC |
| 411 | ZMKT | ZMK TRUCKING | | | SCAC4 |
| 412 | ZMLG | ZOOM LOGISTICS INC | | | SCAC4 |
| 413 | ZMMC | MOBILE MINING & MINERAL CO. | | | PWRC |
| 414 | ZMML | Z&M MOTOR LINE, INC | | | SCAC1 |
| 415 | ZMML | Z & M MOTOR LINE, INC | | | SCAC4 |
| 416 | ZMMR | ZIMMERMA | | | SCAC4 |
| 417 | ZMNU | ZHE JIANG MORITA NEW MATERIALS CO.,LTD | | PRC | BIC |
| 418 | ZMOP | MONSEY PRODUCTS CO. | | | PWRC |
| 419 | ZMOU | ZIM INTEGRATED SHIPPING SERVICES LTD | | IL | BIC |
| 420 | ZMRS | ZOOMERS INC | | | SCAC4 |
| 421 | ZMS | Zweckverband Müllverwertung Schwandorf | | DE | VKM |
| 422 | ZMSI | Z MOTOR SERVICE INC | | | SCAC4 |
| 423 | ZMSU | ZEPPELIN MOBILE SYSTEME GMBH | | D | BIC |
| 424 | ZMTK | ZM TRUCKING LLC | | | SCAC4 |
| 425 | ZMTL | ZIMMERMAN TRUCKING | | | SCAC1 |
| 426 | ZMTL | ZIMMERMAN TRUCK LINES INC | | | SCAC4 |
| 427 | ZMTUB | ZIMTUB SA | | RO | VKM |
| 428 | ZMX | Zummo Meat Co. | 1/1952; eliminated 4/1953 | | NAKINA |
| 429 | ZMX | Zummo Meat Co. | Jan-52 | | NRHS |
| 430 | ZMX | ZUMMO MEAT CO. | | | PWRC |
| 431 | ZMXT | ZMX TRANSPORTATION SERVICES INC | | | SCAC4 |
| 432 | ZMYU | TIAN HAO WAREHOUSING AND TRANSPORTATION | | HK | BIC |
| 433 | ZMZ | Zubrnická museální železnice | | CZ | VKM |
| 434 | ZN | Compagnie Aerienne Corse Mediterranee | ICAO: CCM, Callsign: Corsemedi, Established on 01 January 1989. Commenced operations in June 1990. IATA designator changed to XK | F | AVCODES |
| 435 | ZN | Eagle Airlines Luftverkehrsges mbH | ICAO: EAV, Callsign: Mayflower, Designator ZN recalled by IATA | A | AVCODES |
| 436 | ZN | Air Bourbon | ICAO: BUB, Callsign: Bourbon, Commenced operations on 07 June 2003. Ceased operations in December 2004. | REU | AVCODES |
| 437 | ZN | Zambia Airways (2014) Limited | ICAO: AZB, Callsign: Air Zambia, IATA Prefix: 138, | Z | AVCODES |
| 438 | ZNCK | ZERNICKE TRUCKING INC | | | SCAC4 |
| 439 | ZNDH | Air Force of the Independent State of Croatia (Zrakoplovstvo Nezavisne Države Hrvatske) | | NDH | TRAFFIC |
| 440 | ZNDL | ZINKE DRAY LINE, INC | | | SCAC1 |
| 441 | ZNDL | ZINKE DRAY LINE INC | | | SCAC4 |
| 442 | ZNGW | ZINGER WINGER INC | | | SCAC4 |
| 443 | ZNHC | ZEN-NOH HAY INC | | | SCAC4 |
| 444 | ZNLEP | Newag Gliwice S.A. | | PL | VKM |
| 445 | ZNS | Zakład Naprawy Samochodów Ryszard Elszyn | City: Solec Kujawski | PL | TRAFFIC |
| 446 | ZNSC | ZENITH LOGISTICS (USA) INC | | | SCAC4 |
| 447 | ZNSU | NORFOLK SOUTHERN CORPORATION | | | SCAC4 |
| 448 | ZNTE | ZUNIGA TOVAR, LETICIA | | | SCAC4 |
| 449 | ZNTG | ZENTNER TRANSPORTATION INC | | | SCAC4 |
| 450 | ZNTI | ZENITH INC | | | SCAC4 |
| 451 | ZNZF | ZERO NINE ZERO FIVE TWO ZERO ZERO S | | | SCAC4 |
| 452 | ZNZU | ZANZIBAR SHIPPING LINES LIMITED | | EAT | BIC |
| 453 | ZO | Ozark Air Lines, Inc. d/b/a/ Great Plains Airlines | ICAO: GRP, Callsign: Great Plains, Name changed from Ozark Air Lines, Inc. Founded in 2001. Ceased operations in 2004. ICAO designator changed from OZR | USA | AVCODES |
| 454 | ZO | Ozark Air Lines, Inc. | ICAO: OZR, Name changed to Ozark Air Lines, Inc. d/b/a Great Plains Airlines. ICAO designator changed to GRP | USA | AVCODES |
| 455 | ZO | Air Georgian Ltd. d/b/a Air Alliance | ICAO: GGN, Callsign: Georgian, IATA designator changed to ZX | CDN | AVCODES |
| 456 | ZO | Central Air Transpsort Services | ICAO: CEN, Callsign: Shumba, | ZW | AVCODES |
| 457 | ZO | M/S Zexus Air Services Pvt. Ltd t/a Zoom Air | ICAO: ZOM, Callsign: Zoom, Designator ZO recalled by IATA. DGCA licence approved. Commence domestic operations in February 2017. | IND | AVCODES |
| 458 | ZO | Colorful Yunnan General Aviation Co., Ltd. t/a Colorful Yunnan Airlines | | PRC | AVCODES |
| 459 | ZÖA | Zweckverband Öffentlicher Nahverkehr im Ammertal | Tübingen | D | privat-bahn.de |
| 460 | ZOB | Zollernbahn | | D | TRAFFIC |
| 461 | ZOBR | ZOBRIST, NEAL L INC | | | SCAC4 |
| 462 | ZOCC | OCCIDENTAL CHEMICAL | | | PWRC |
| 463 | ZOCI | ZOCALO IMPORTS INC | | | SCAC4 |
| 464 | ZOCO | ZIEGLER OIL CO | | | SCAC4 |
| 465 | ZODA | ZORMAN, DALE A TRUCKING SERVICE INC | | | SCAC4 |
| 466 | ZODY | ZODYS MOVING & STORAGE INC | | | SCAC4 |
| 467 | ZOES | ZOES TROPICALS INC | | | SCAC4 |
| 468 | ZOGJ | ZOT LUXURY LOGISTICS INC | | | SCAC4 |
| 469 | ZOIC | ZOLLICKER OIL CO INC | | | SCAC4 |
| 470 | ZOLA | ZOLA ENTERPRISES CO LTD | | | SCAC4 |
| 471 | ZOM | M/S Zexus Air Services Pvt. Ltd t/a Zoom Air | IATA: ZO, Callsign: Zoom, Designator ZO recalled by IATA. DGCA licence approved. Commence domestic operations in February 2017. | IND | AVCODES |
| 472 | ZOM | M/S Zexus Air Services Pvt. Ltd t/a Zoom Air | Callsign: Zoom, Designator ZO recalled by IATA. DGCA licence approved. Commence domestic operations in February 2017. | IND | AVCODES |
| 473 | ZOMA | ZODIAC MARITIME AGENCIES LTD | | | SCAC4 |
| 474 | ZOMT | ZOOM TRANSPORT INC | | | SCAC4 |
| 475 | ZONT | ZONE TRANSPORTATION COMPANY | | | SCAC4 |
| 476 | ZOOK | ZOOK TRUCKING LLC | | | SCAC4 |
| 477 | ZOS | ZOS Zvolen s.r.o. | | SK | TRAFFIC |
| 478 | ZOS | ZOS ZVOLEN s.r.o. | | SK | VKM |
| 479 | ZOSTT | ŽOS Trnava, a.s. | | SK | VKM |
| 480 | ZOSVR | ŽOS Vrútky a.s. | | SK | VKM |
| 481 | ZOSZV | Železničné opravovne a strojárne Zvolen, a.s. | | SK | VKM |
| 482 | ZOUD | ZOUDIS, PANAYOTE | | | SCAC4 |
| 483 | ZOYA | ZOYA VENTURES | | | SCAC4 |
| 484 | ZP | Air St. Thomas | ICAO: STT, Callsign: Paradise, Designator ZP recalled by IATA. ceased operations in December 2005 | VI | AVCODES |
| 485 | ZP | Silk Way Airlines | ICAO: AZQ, Callsign: Silk Line, IATA Prefix: 463, | AZ | AVCODES |
| 486 | ZP | Amaszonas del Paraguay SA Lineas Aereas | ICAO: AZP, Callsign: Guarani, Name changed to Compa��a de Aviaci�n Paraguaya S.A. d/b/a Paranair w.e.f. from 15 October 2018. | PY | AVCODES |
| 487 | ZP | Compañía de Aviación Paraguaya S.A. d/b/a Paranair | ICAO: AZP, Callsign: Guarani, IATA Prefix: 445, Name changed from Amaszonas del Paraguay SA Lineas Aereas w.e.f. from 15 October 2018. | PY | AVCODES |
| 488 | ZPCA | ZIP CARRIERS INC | | | SCAC4 |
| 489 | ZPCI | ZAPATA TRUCKING | | | SCAC4 |
| 490 | ZPCN | ZUNIGA PEREZ, CARLOS NOE | | | SCAC4 |
| 491 | ZPCR | ZYGOTE PRO-CREATIONS INC | | | SCAC4 |
| 492 | ZPDY | ZIPP DELIVERY INC | | | SCAC4 |
| 493 | ZPHY | ZEPHYR TRUCKING INC | | | SCAC4 |
| 494 | ZPLU | KONRAD ZIPPEL SPEDITEUR GMBH & CO. KG | | D | BIC |
| 495 | ZPNT | Zakłady Produkcyjno-Naprawcze Taboru Maszyn i Urządzeń TABOR M. Dybowski sp. j. | | PL | VKM |
| 496 | ZPORT | ZÁHONY-PORT Zrt. (ZÁHONY-PORT Co) | | HU | VKM |
| 497 | ZPRG | ZAPATA RAMIREZ, GERARDO | | | SCAC4 |
| 498 | ZPRU | Caribbean Shipping Services | | | RSRV |
| 499 | ZPRU | CARIBBEAN SHIPPING SERVICES | | | SCAC4 |
| 500 | ZPS | ZAKLAD PREWOZÓW I SPEDYCJI \'\'SPEDKOKS\'\' SP. Z.O.O. | | PL | VKM |
