| 1 | S | | City: Stuttgart | D | TRAFFIC |
| 2 | S&L | Sydney & Louisburg Ry. | 7/1923-4/1961 | | NAKINA |
| 3 | S&L | Cumberland Ry. | 7/1965 | | NAKINA |
| 4 | S&L | Sydney & Louisburg Ry. | 4/38-4/61 | | NRHS |
| 5 | S&L | Cumberland Ry. | Jul-65 | | NRHS |
| 6 | S&L | *SYDNEY & LOUISBURG RWY. | | | PWRC |
| 7 | S&L | *CUMBERLAND RWY. | | | PWRC |
| 8 | S&NJ | Sveriges & Norges Järnvägar AB | 1888 - 1891 | S | svenska-lok.se |
| 9 | S&NW | Savannah & Northwestern Ry. (Savannah & Atlanta Ry.) | 8/1920 | | NAKINA |
| 10 | S&NW | SAVANNAH & ATLANTA RWY. [SAVANNAH & NORTHWESTERN RWY.] | | | PWRC |
| 11 | S&NY | Susquehanna & New York R.R. Co. | 7/1923-1/1941 | | NAKINA |
| 12 | S&NY | Susquehanna & New York R.R. Co. | Apr-38 | | NRHS |
| 13 | S&NY | SUSQUEHANNA & NEW YORK RAILROAD CO. | | | PWRC |
| 14 | S&T | Sheffield & Tionesta Ry. | 4/1938-7/1954 | | NAKINA |
| 15 | S&T | Sheffield & Tionesta Ry. | 4/38-1/52 | | NRHS |
| 16 | S&T | SHEFFIELD & TIONESTA RWY. | | | PWRC |
| 17 | S&W | New York, Susquehanna & Western R.R. Co. | 7/1923-7/1936 | | NAKINA |
| 18 | S&W | New York, Susquehanna & Western R.R. | 4/1938-10/1957 | | NAKINA |
| 19 | S&W | New York, Susquehanna & Western R.R. | 4/38-10/57 | | NRHS |
| 20 | S&W | NEW YORK, SUSQUEHANNA & WESTERN RR | | | PWRC |
| 21 | S0 | Slok Air International (Gambia) Limited | ICAO: OKS, Name changed from Slok Air International. Incorporated on 17th September 1996. Commenced operations on 24th of September 2004. | WAG | AVCODES |
| 22 | S0 | Slok Air International | ICAO: OKS, Name changed to Slok Air International (Gambia) Limited | WAG | AVCODES |
| 23 | S0 | Aerolineas Sosa, S.A. de C.V. | | MEX | AVCODES |
| 24 | S1 | Lufthansa Systems AG | Name changed to Lufthansa Systems GmbH & Co. KG. Computer Reservation Systems (CRS) | D | AVCODES |
| 25 | S1 | Lufthansa Systems GmbH & Co. KG | Name changed from Lufthansa Systems AG. Computer Reservation Systems (CRS) | D | AVCODES |
| 26 | S2 | Sahara Airlines Limited | ICAO: SHD, Name changed from Sahara India Airlines Ltd. | IND | AVCODES |
| 27 | S2 | Sahara India Airlines Ltd. | ICAO: SHD, Name changed to Sahara Airlines Limited | IND | AVCODES |
| 28 | S2 | Jet Lite (India) Limited | ICAO: JLL, Callsign: Lite Jet, IATA Prefix: 705, Name changed to JetKonnect on 25 March 2012. Name changed from Sahara Airlines Limited on 16 April 2007. ICAO designator changed from RSH | IND | AVCODES |
| 29 | S2 | Jet Lite (India) Limited | ICAO: RSH, Callsign: Lite Jet, IATA Prefix: 705, Name changed from Sahara Airlines Limited. ICAO designator changed to JLL. Name changed from Sahara India Airlines Ltd. | IND | AVCODES |
| 30 | S2 | Sahara Airlines Limited t/a Air Sahara | ICAO: SHD, Name changed to Jet Lite (India) Limited. ICAO code JLL. Name changed from Sahara India Airlines Ltd. | IND | AVCODES |
| 31 | S2 | JetKonnect | ICAO: JLL, Callsign: Lite Jet, IATA Prefix: 705, Name changed from Jet Lite (India) Limited on 25 March 2012. Name changed from Sahara Airlines Limited on 16 April 2007. ICAO designator changed from RSH | IND | AVCODES |
| 32 | S2 | JetKonnect | ICAO: JLL, Callsign: Lite Jet, IATA Prefix: 705, Temporarily suspended operations on 17 April 2019. Name changed from Jet Lite (India) Limited on 25 March 2012. Name changed from Sahara Airlines Limited on 16 April 2007. ICAO designator changed from RSH | IND | AVCODES |
| 33 | S2 | Sapsan Airlines d/b/a SAPSAN Airline | ICAO: KGB, Callsign: Sapsan, IATA Prefix: 708, | KS | AVCODES |
| 34 | S2 | Serve Air S.a.r.l. | | ZRE | AVCODES |
| 35 | S3 | Santa Barbara Airlines, C.A. | ICAO: BBR, Callsign: Santa Barbara, AOC suspended on 31 January 2018. IATA designator changed from BJ* | YV | AVCODES |
| 36 | S3 | San Air Company | Designator S3* reinstated by IATA | KZ | AVCODES |
| 37 | S3 | TOO Sunkar Air | ICAO: KAM, Callsign: Sunkar, | KZ | AVCODES |
| 38 | S3 | SATCO, Inc. | Non-airline Unit Load Devices (ULD) companies | USA | AVCODES |
| 39 | S4 | SATA International Servicos e Transportes Aereos, S.A. | ICAO: RZO, Callsign: Air Azores, IATA Prefix: 331, Name changed to SATA International Servicos e Transportes Aereos, S.A. t/a Azores Airlines | P | AVCODES |
| 40 | S4 | SATA International Servicos e Transportes Aereos, S.A. t/a Azores Airlines | ICAO: RZO, Callsign: Air Azores, IATA Prefix: 331, Name changed from SATA International Servicos e Transportes Aereos, S.A. | P | AVCODES |
| 41 | S5 | Shuttle America | ICAO: TCF, Callsign: Shuttlecraft, Name changed to Shuttle America Corporation. ICAO callsign changed to Mercury. Designator S5 reinstated by IATA. Operates as US Airways Express | USA | AVCODES |
| 42 | S5 | Saeaga Airlines | ICAO: SGG, Callsign: Saeaga, Designator S5 recalled by IATA | MAL | AVCODES |
| 43 | S5 | Trast Aero | ICAO: TSJ, | KS | AVCODES |
| 44 | S5 | Shuttle America Corporation | ICAO: TCF, Callsign: Mercury, Merged into Republic Airline on 31 January 2017. Name changed from Shuttle America. ICAO callsign changed from Shuttlecraft. Designator S5 reinstated by IATA. Operates as US Airways Express | USA | AVCODES |
| 45 | S5 | Small Planet Airlines UAB | ICAO: LLC, Callsign: Small Planet, Ceased operations on 28 November 2018. | LT | AVCODES |
| 46 | S5 | Abakan Air LLC | ICAO: NKP, Callsign: Abakan Air, IATA Prefix: 917, | RUS | AVCODES |
| 47 | S5 | Ghodawat Enterprises Pvt. Ltd. d/b/a Ghodawat Aviation | ICAO: SDG, Callsign: Hi Star, Name changed to Ghodawat Enterprises Pvt. Ltd. d/b/a Star Air. IATA designator changed from OG*. | IND | AVCODES |
| 48 | S5 | Ghodawat Enterprises Pvt. Ltd. d/b/a Star Air | ICAO: SDG, Callsign: Hi Star, Name changed from Ghodawat Enterprises Pvt. Ltd. d/b/a Ghodawat Aviation. IATA designator changed from OG*. | IND | AVCODES |
| 49 | S6 | Mountain Bird, Inc. d/b/a Salmon Air | | USA | AVCODES |
| 50 | S6 | SAE SWE Aviation Europe AB | IATA designator changed to S9* | S | AVCODES |
| 51 | S6 | Air St. Martin | Designator recalled by IATA | GP | AVCODES |
| 52 | S6 | SiFly Compagnia Aerea | ICAO: KWY, Callsign: Sifly, Designator S6 recalled by IATA | I | AVCODES |
| 53 | S6 | SiFly Compagnia Aerea | ICAO: KWY, Callsign: Sifly, Ceased operations on 06 October 2001. Designator S6 reinstated by IATA | I | AVCODES |
| 54 | S6 | Star Air A/S | ICAO: SRR, Callsign: Whitestar, IATA designator changed to DJ*. | DK | AVCODES |
| 55 | S6 | Sun Air Co. | ICAO: SNR, Callsign: Sun Group, Designator S6 recalled by IATA. | SUD | AVCODES |
| 56 | S6 | McCall Aviation, Inc. | ICAO: MKL, Callsign: Mccall, | USA | AVCODES |
| 57 | S6 | Sunrise Airways S.A. | ICAO: KSZ, | RH | AVCODES |
| 58 | S7 | S7 Airlines. Siberia Airlines JSC | ICAO: SBI, Callsign: Siberian Airlines, IATA Prefix: 421, Name changed from Siberia Airlines - Sibir Airlines. ICAO callsign hanged from Siberia Airlines | RUS | AVCODES |
| 59 | S7 | Siberia Airlines PJSC | ICAO: SBI, Callsign: Siberian Airlines, IATA Prefix: 421, Name changed from S7 Airlines. Siberia Airlines JSC. Name changed from Siberia Airlines - Sibir Airlines. ICAO callsign hanged from Siberia Airlines | RUS | AVCODES |
| 60 | S7 | JSC Siberia Airlines d/b/a S7 Airlines | ICAO: SBI, Callsign: Siberian Airlines, IATA Prefix: 421, Name changed from Siberia Airlines PJSC and previously from S7 Airlines. Siberia Airlines JSC. Name changed from Siberia Airlines - Sibir Airlines. ICAO callsign hanged from Siberia Airlines | RUS | AVCODES |
| 61 | S8 | Estonian Aviation Company ELK Airways | ICAO: ELK, Callsign: Elka, IATA Prefix: 520, Designator S8 recalled by IATA | EST | AVCODES |
| 62 | S8 | Shovkoviy Shlyah Ltd. Airlines | ICAO: SWW, Callsign: Way Aero, | UA | AVCODES |
| 63 | S8 | Chari Aviation Services | ICAO: CAH, Callsign: Charlan, ceased operations on 26 May 2006. Designator S8* recalled by IATA | ZA | AVCODES |
| 64 | S8 | Sama Air LLC | | UAE | AVCODES |
| 65 | S8 | Cabolar (Pty) Ltd t/a Skywise | ICAO: SWZ, Callsign: Skywise, Designator S8 recalled by IATA. Low cost airlines planned to start operations in 2013 from the founder of 1Time Airlines | ZA | AVCODES |
| 66 | S8 | Sounds Air Travel & Tourism Ltd. | ICAO: SDA, | NZ | AVCODES |
| 67 | S8 | Sky Capital Airlines Ltd. t/a SkyAir | ICAO: AHW, IATA Prefix: 442, Designator S8* recalled by IATA. | BD | AVCODES |
| 68 | S8 | Sky Capital Airlines Ltd. | ICAO: AHW, Callsign: Sky Capital, IATA Prefix: 442, Founded in 2009. Commenced operations on 26 January 2010. | BD | AVCODES |
| 69 | S9 | Transjet Airways AB | ICAO: SWL, Callsign: Transjet, Operating Licence revoked on 09 July 2002. Name changed from SAE SWE Aviation Europe AB / Callsign changed. IATA changed from S6* | S | AVCODES |
| 70 | S9 | SK Air a.s. | ICAO: SKU, Callsign: Eska, | SK | AVCODES |
| 71 | S9 | SAE SWE Aviation Europe AB | ICAO: SWL, Callsign: Swing, Name changed to Trans Jet Airways AB / Callsign changed. IATA changed from S6* | S | AVCODES |
| 72 | S9 | East African Safari Air Limited | ICAO: HSA, Callsign: Car Hire, IATA Prefix: 895, ICAO Callsign changed to Duma. IATA designator changed from RX*. Name changed from CHS Aviation Limited | EAK | AVCODES |
| 73 | S9 | East African Safari Air Limited | ICAO: HSA, Callsign: Duma, IATA Prefix: 895, Ceased operations. ICAO Callsign changed from Car Hire. IATA designator changed from RX*. Name changed from CHS Aviation Limited | EAK | AVCODES |
| 74 | S9 | Sky Air World | ICAO: SYW, Callsign: Sky Air, IATA Prefix: 535, Founded in 2006. Ceased operations on 22 February 2009. | AUS | AVCODES |
| 75 | S9 | Aero Survey Ltd t/a Starbow | ICAO: IKM, Callsign: Easy Shuttle, IATA Prefix: 759, Name changed from Aero Survey Ltd. ICAO callsign changed from Ghana Survey | GH | AVCODES |
| 76 | S9 | Air Company LLC Silk Road Cargo Business | ICAO: URS, Callsign: Silk Cargo, IATA Prefix: 939, | UZ | AVCODES |
| 77 | S9 | Big Charter Pvt. Ltd. d/b/a FlyBig | ICAO: FLG, Callsign: Krish, Commenced operations on 21 December 2020. | IND | AVCODES |
| 78 | SA | South African Airways SOC Limited | ICAO: SAA, Callsign: Springbok, IATA Prefix: 083, | ZA | AVCODES |
| 79 | SA | Air Company Sirius-Aero Ltd | ICAO: CIG, Callsign: Sirius Aero, | RUS | AVCODES |
| 80 | SA | Norfolk Southern Ry. Co. (Norfolk Southern) | 7/2005 | | NAKINA |
| 81 | SA | Norfolk Southern Ry. Co. | added 1/1991; 1/1994-7/2000 | | NAKINA |
| 82 | SA | Southern Ry. System | eliminated 1/1991 | | NAKINA |
| 83 | SA | Central of Georgia R.R. Co. | 1/1975-1/1980 | | NAKINA |
| 84 | SA | Savannah & Atlanta Ry. Co. | 4/1938-4/1970 | | NAKINA |
| 85 | SA | Savannah & Atlanta Ry. Co. | 4/38-4/70 | | NRHS |
| 86 | SA | Central of Georgia R.R. Co. | 1/75-1/80 | | NRHS |
| 87 | SA | Southern Ry. System | eliminated 1/91 | | NRHS |
| 88 | SA | Norfolk Southern Ry. Co. | added 1/91; 1/94-7/2000 | | NRHS |
| 89 | SA | NORFOLK SOUTHERN [SOUTHERN; CENTRAL OF GEORGIA; SAVANNAH & ATLANTA RY] | | | PWRC |
| 90 | SA | Savannah and Atlanta Railroad (Central of Georgia Railroad) | | | RSRV |
| 91 | SA | SAVANNAH & ATLANTA RAILWAY | | | SCAC4 |
| 92 | SA | Savannah & Atlanta Ry. Co. | | USA | TRAFFIC |
| 93 | SAA | South African Airways SOC Limited | IATA: SA, Callsign: Springbok, IATA Prefix: 083, | ZA | AVCODES |
| 94 | SAA | South African Airways | IATA: SA | | ICAO1 |
| 95 | SAA | The San Antonio and Aransas Pass Ry. Co. | 7/1923 | | NAKINA |
| 96 | SAA | SAN ANTONIO & ARANSAS PASS RWY. CO. | | | PWRC |
| 97 | SAA | South African Army | | ZA | TRAFFIC |
| 98 | SAAA | SADA TRANSPORT | | | SCAC4 |
| 99 | SAAC | SANTIAGO & ASSOCIATES INC | | | SCAC4 |
| 100 | SAAE | SANDHU LOGISTIC CARRIER | | | SCAC4 |
